A8AWT7 (WHIA_STRGC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative sporulation transcription regulator WhiA

Gene names

Name:	whiA
Ordered Locus Names:	SGO_0956

Organism

Streptococcus gordonii (strain Challis / ATCC 35105 / CH1 / DL1 / V288) [Complete proteome] [HAMAP]

Taxonomic identifier

29390 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus › Streptococcus gordonii

Protein attributes

Sequence length	303 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May be required for sporulation By similarity.
Sequence similarities	Belongs to the WhiA transcriptional regulatory family.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Ligand	DNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	regulation of sporulation Inferred from electronic annotation. Source: HAMAP regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 303	303	Putative sporulation transcription regulator WhiA HAMAP-Rule MF_01420		PRO_0000376574
Regions
	DNA binding	272 – 303	32	H-T-H motif Potential

Sequences

	Sequence		Length	Mass (Da)
	A8AWT7 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: F0FFE3C5C278C1BB	FASTA	303	33,906
	10 20 30 40 50 60 MSFTVKVKEE LLGLGTKSKS ELAAIMKMSG SLGIASQGLT LSITTENAKI ARHIYELLLS 70 80 90 100 110 120 FYQVKSDIRH HQKTNLRKNR VYTVFLDEKV EDILSDLHLA DAFFGIQEGI DPLILSDDEA 130 140 150 160 170 180 SRAYLRGAFL SNGSMRDPES GKYQLEIVSV YLDHAQGLAS LMQRFLLDAK TIERKKGAVT 190 200 210 220 230 240 YLQRAEDIMD FLIVVGAMEA MAEFEAVKIL RETRNDLNRA NNAETANIAR TVTASMKTIN 250 260 270 280 290 300 NIVKIMETSG LENLPIDLQE VAHLRVNHPD YSIQQLADSL SKPLTKSGVN HRLRKINKIA DEL

References

[1]

"Genome-wide transcriptional changes in Streptococcus gordonii in response to competence signaling peptide." Vickerman M.M., Iobst S., Jesionowski A.M., Gill S.R. J. Bacteriol. 189:7799-7807(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Challis / ATCC 35105 / CH1 / DL1 / V288.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000725 Genomic DNA. Translation: ABV09711.1.
RefSeq	YP_001450247.1. NC_009785.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	467705.SGO_0956.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABV09711; ABV09711; SGO_0956.
GeneID	5597871.
KEGG	sgo:SGO_0956.
PATRIC	19659865. VBIStrGor124371_0939.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1481.
HOGENOM	HOG000040187.
KO	K09762.
OMA	DSFFGIE.
ProtClustDB	CLSK877081.
Enzyme and pathway databases
BioCyc	SGOR467705:GH3R-1012-MONOMER.
Family and domain databases
HAMAP	MF_01420. HTH-type_WhiA.
InterPro	IPR003802. Sporulation_regulator_WhiA. IPR023054. Sporulation_regulator_WhiA_C. IPR018478. Sporulation_regulator_WhiA_N. [Graphical view]
Pfam	PF02650. HTH_WhiA. 1 hit. PF10298. WhiA_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00647. MG103. 1 hit.
ProtoNet	Search...

Entry information

Entry name

WHIA_STRGC

Accession

Primary (citable) accession number: A8AWT7

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 26, 2009
Last sequence update:	October 23, 2007
Last modified:	May 1, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program