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A8AW04

- TRPF_STRGC

UniProt

A8AW04 - TRPF_STRGC

Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Streptococcus gordonii (strain Challis / ATCC 35105 / CH1 / DL1 / V288)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (23 Oct 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tryptophan biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

    Enzyme and pathway databases

    BioCyciSGOR467705:GH3R-660-MONOMER.
    UniPathwayiUPA00035; UER00042.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
    Short name:
    PRAIUniRule annotation
    Gene namesi
    Name:trpFUniRule annotation
    Ordered Locus Names:SGO_0661
    OrganismiStreptococcus gordonii (strain Challis / ATCC 35105 / CH1 / DL1 / V288)
    Taxonomic identifieri29390 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000001131: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 195195N-(5'-phosphoribosyl)anthranilate isomerasePRO_1000076441Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi467705.SGO_0661.

    Structurei

    3D structure databases

    ProteinModelPortaliA8AW04.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrpF family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0135.
    HOGENOMiHOG000161598.
    KOiK01817.
    OMAiDILQLHG.
    OrthoDBiEOG6N94DF.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00135. PRAI.
    InterProiIPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00697. PRAI. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A8AW04-1 [UniParc]FASTAAdd to Basket

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    MTKVKICGLS TASAVETACQ AGADYIGFVF AESRRRVSLE QAQKLAALVP    50
    STVRKVGVFV SPSLAELQEA ISVANLDLVQ IHGDFDEELL TQIDRPVIQA 100
    YQVKGALKDV SQQADYLLFD APLAGSGRTF DWQAFDKSQI HQPFFIAGGL 150
    NAGNVREAIQ HFAPYAVDVS SGVETDAQKD LEKIKEFIER VKDGI 195
    Length:195
    Mass (Da):21,231
    Last modified:October 23, 2007 - v1
    Checksum:i356E671FB1430BFF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000725 Genomic DNA. Translation: ABV09399.1.
    RefSeqiYP_001449964.1. NC_009785.1.

    Genome annotation databases

    EnsemblBacteriaiABV09399; ABV09399; SGO_0661.
    GeneIDi5599014.
    KEGGisgo:SGO_0661.
    PATRICi19659285. VBIStrGor124371_0650.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000725 Genomic DNA. Translation: ABV09399.1 .
    RefSeqi YP_001449964.1. NC_009785.1.

    3D structure databases

    ProteinModelPortali A8AW04.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 467705.SGO_0661.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABV09399 ; ABV09399 ; SGO_0661 .
    GeneIDi 5599014.
    KEGGi sgo:SGO_0661.
    PATRICi 19659285. VBIStrGor124371_0650.

    Phylogenomic databases

    eggNOGi COG0135.
    HOGENOMi HOG000161598.
    KOi K01817.
    OMAi DILQLHG.
    OrthoDBi EOG6N94DF.

    Enzyme and pathway databases

    UniPathwayi UPA00035 ; UER00042 .
    BioCyci SGOR467705:GH3R-660-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00135. PRAI.
    InterProi IPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00697. PRAI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome-wide transcriptional changes in Streptococcus gordonii in response to competence signaling peptide."
      Vickerman M.M., Iobst S., Jesionowski A.M., Gill S.R.
      J. Bacteriol. 189:7799-7807(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Challis / ATCC 35105 / CH1 / DL1 / V288.

    Entry informationi

    Entry nameiTRPF_STRGC
    AccessioniPrimary (citable) accession number: A8AW04
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: October 23, 2007
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3