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A8AUB1

- A8AUB1_STRGC

UniProt

A8AUB1 - A8AUB1_STRGC

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Protein

Aldose 1-epimerase

Gene
galM, SGO_0049
Organism
Streptococcus gordonii (strain Challis / ATCC 35105 / CH1 / DL1 / V288)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose By similarity.UniRule annotation

Catalytic activityi

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. aldose 1-epimerase activity Source: UniProtKB-EC
  2. carbohydrate binding Source: InterPro

GO - Biological processi

  1. hexose metabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationImported

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

BioCyciSGOR467705:GH3R-49-MONOMER.
UniPathwayiUPA00242.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
Alternative name(s):
Galactose mutarotase
Gene namesi
Name:galMImported
Ordered Locus Names:SGO_0049Imported
OrganismiStreptococcus gordonii (strain Challis / ATCC 35105 / CH1 / DL1 / V288)
Taxonomic identifieri29390 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000001131: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi467705.SGO_0049.

Structurei

3D structure databases

ProteinModelPortaliA8AUB1.

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000072798.
KOiK01785.
OMAiFEAQCPP.
OrthoDBiEOG69WFM5.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8AUB1-1 [UniParc]FASTAAdd to Basket

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MKSYQKTIFG EFQGQNIFRF TFENDLGYRL SVMNYGATIL EYQTPDKKGQ    50
FANVILGFDQ FEDYIGNSPK HGASIGPVAG RIAGASFELG GEIYHLEANN 100
GQNCNHSGST GWDSTVFQVE EVTDEGLVLF TERADGTGGF PGHLKVWISY 150
TLSEKGELEI SYQVQTDRDT LINPTNHSYF NLSADFAQSI DDHVFQVDSL 200
GFYPIAEDGV PAKETEISDF VKHLQQAMLL KDLFAEKDEQ VRLVSGLDHP 250
FALKPGHETA GFLYHQESGR FLTFKTEAPC LVVYTANCVD EAIRFGGQTM 300
KQHNGVALEM QALPDAIHSH QKDQVIVRAG QEFTSTTTYH AIAK 344
Length:344
Mass (Da):38,246
Last modified:October 23, 2007 - v1
Checksum:i36F1D2DA60ABD1A6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000725 Genomic DNA. Translation: ABV10531.1.
RefSeqiYP_001449371.1. NC_009785.1.

Genome annotation databases

EnsemblBacteriaiABV10531; ABV10531; SGO_0049.
GeneIDi5598923.
KEGGisgo:SGO_0049.
PATRICi19658051. VBIStrGor124371_0047.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000725 Genomic DNA. Translation: ABV10531.1 .
RefSeqi YP_001449371.1. NC_009785.1.

3D structure databases

ProteinModelPortali A8AUB1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 467705.SGO_0049.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABV10531 ; ABV10531 ; SGO_0049 .
GeneIDi 5598923.
KEGGi sgo:SGO_0049.
PATRICi 19658051. VBIStrGor124371_0047.

Phylogenomic databases

HOGENOMi HOG000072798.
KOi K01785.
OMAi FEAQCPP.
OrthoDBi EOG69WFM5.

Enzyme and pathway databases

UniPathwayi UPA00242 .
BioCyci SGOR467705:GH3R-49-MONOMER.

Family and domain databases

Gene3Di 2.70.98.10. 1 hit.
InterProi IPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view ]
Pfami PF01263. Aldose_epim. 1 hit.
[Graphical view ]
PIRSFi PIRSF005096. GALM. 1 hit.
SUPFAMi SSF74650. SSF74650. 1 hit.
PROSITEi PS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome-wide transcriptional changes in Streptococcus gordonii in response to competence signaling peptide."
    Vickerman M.M., Iobst S., Jesionowski A.M., Gill S.R.
    J. Bacteriol. 189:7799-7807(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Challis / ATCC 35105 / CH1 / DL1 / V288.

Entry informationi

Entry nameiA8AUB1_STRGC
AccessioniPrimary (citable) accession number: A8AUB1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 23, 2007
Last sequence update: October 23, 2007
Last modified: June 11, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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