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Protein

Ribosomal RNA large subunit methyltransferase G

Gene

rlmG

Organism
Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N2-methylguanine(1835) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciCKOS290338:G1G9Z-3944-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase GUniRule annotation (EC:2.1.1.174UniRule annotation)
Alternative name(s):
23S rRNA m2G1835 methyltransferaseUniRule annotation
rRNA (guanine-N(2)-)-methyltransferase RlmGUniRule annotation
Gene namesi
Name:rlmGUniRule annotation
Ordered Locus Names:CKO_04488
OrganismiCitrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
Taxonomic identifieri290338 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeCitrobacter
Proteomesi
  • UP000008148 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003664491 – 378Ribosomal RNA large subunit methyltransferase GAdd BLAST378

Proteomic databases

PRIDEiA8APY0

Interactioni

Protein-protein interaction databases

STRINGi290338.CKO_04488

Structurei

3D structure databases

ProteinModelPortaliA8APY0
SMRiA8APY0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. RlmG family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D8J Bacteria
COG2813 LUCA
HOGENOMiHOG000246323
KOiK11391
OMAiNLQAWDA
OrthoDBiPOG091H05RK

Family and domain databases

HAMAPiMF_01859 23SrRNA_methyltr_G, 1 hit
InterProiView protein in InterPro
IPR002052 DNA_methylase_N6_adenine_CS
IPR017237 rRNA_m2G-MeTrfase_RsmD
IPR029063 SAM-dependent_MTases
IPR007848 Small_mtfrase_dom
PANTHERiPTHR18895:SF6 PTHR18895:SF6, 1 hit
PfamiView protein in Pfam
PF05175 MTS, 1 hit
PIRSFiPIRSF037565 RRNA_m2G_Mtase_RsmD_prd, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit

Sequencei

Sequence statusi: Complete.

A8APY0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHVDNGFRS LTLKRFPETD DVNPLQAWEA ADEYLLQQLD DTEISGPLLI
60 70 80 90 100
LNDAFGALSC ALAEHTPYSI GDSYLSELAT RENLRHNDIA ESSVKFLDST
110 120 130 140 150
AAYPPAPGVV LIKVPKTLAL LEQQLRALRQ VVTPQTRIIA GAKARDIHTS
160 170 180 190 200
TLELFEKVLG PTTTTLAWKK ARLINCTFSK PELADAPQTL SWKLDGTDWT
210 220 230 240 250
IHNHANVFSR TGLDIGARFF MQHLPENLEG EIVDLGCGNG VIGLTLLAKN
260 270 280 290 300
PQASVVFVDE SPMAVASSRL NVETNMPEAL DRCEFMINNA LSGVEPFRFN
310 320 330 340 350
AVLCNPPFHQ KHALTDNVAW EMFHHARRCL KINGELYIVA NRHLDYFHKL
360 370
KKIFGNCTTI ATNNKFVVLK AVKTGRRR
Length:378
Mass (Da):42,098
Last modified:October 23, 2007 - v1
Checksum:iD865496D29D15903
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000822 Genomic DNA Translation: ABV15543.1
RefSeqiWP_012135225.1, NC_009792.1

Genome annotation databases

EnsemblBacteriaiABV15543; ABV15543; CKO_04488
KEGGicko:CKO_04488

Similar proteinsi

Entry informationi

Entry nameiRLMG_CITK8
AccessioniPrimary (citable) accession number: A8APY0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: October 23, 2007
Last modified: May 23, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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