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A8AMN8 (PSD_CITK8) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:CKO_03674
OrganismCitrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696) [Complete proteome] [HAMAP]
Taxonomic identifier290338 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Citrobacter

Protein attributes

Sequence length322 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00662

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 253253Phosphatidylserine decarboxylase beta chain By similarity
PRO_1000026540
Chain254 – 32269Phosphatidylserine decarboxylase alpha chain By similarity
PRO_1000026541

Sites

Site253 – 2542Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2541Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
A8AMN8 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: 9A837FCB2893DBDF

FASTA32235,967
        10         20         30         40         50         60 
MLNSFKLSLQ YILPKLWLTR LAGWGARKRA GWLTKLVIDL FVKYYKVDMK EAQKPDTASY 

        70         80         90        100        110        120 
RTFNDFFVRP LRDDVRPVNT DPNVLVMPAD GVISQSGKIE EDKILQAKGH NYSLEALLAG 

       130        140        150        160        170        180 
NYLMADLFRN GSFVTTYLSP RDYHRVHMPC NGILREMIYV PGDLFSVNHL TAQNVPNLFA 

       190        200        210        220        230        240 
RNERVICLFD TEFGPMAQIL VGATIVGSIE TVWAGTITPP REGVIKRWTW PEGESEGSVA 

       250        260        270        280        290        300 
LLKGQEMGRF KLGSTVINLF APGKVTLAEQ LQSLSVTKIG QPLAVSTELF VTPEAEPAPL 

       310        320 
PEEEINAEHD ASPLVDDKKD ES

« Hide

References

[1]The Citrobacter koseri Genome Sequencing Project
McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R.
Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-895 / CDC 4225-83 / SGSC4696.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000822 Genomic DNA. Translation: ABV14751.1.
RefSeqYP_001455187.1. NC_009792.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA8AMN8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5584261.
GenomeReviewsGene locus CKO_03674 in contig CP000822_GR.
KEGGcko:CKO_03674.
PATRIC20389804. VBICitKos71230_3074.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0688.
HOGENOMHBG302256.
OMASMATVWH.
ProtClustDBPRK00044.

Family and domain databases

HAMAPMF_00662. PS_decarb_type1.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
KOK01613.
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_CITK8
AccessionPrimary (citable) accession number: A8AMN8
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 23, 2007
Last modified: January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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