A8ALY0 (A8ALY0_CITK8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Deoxyribose-phosphate aldolase HAMAP MF_00592
Short name=DERA HAMAP MF_00592
EC=4.1.2.4 HAMAP MF_00592

Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase HAMAP MF_00592
Phosphodeoxyriboaldolase HAMAP MF_00592

Gene names

Name:	deoC HAMAP MF_00592
Ordered Locus Names:	CKO_03410

Organism

Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696) [Complete proteome] [HAMAP]

Taxonomic identifier

290338 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Citrobacter

Protein attributes

Sequence length	265 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. SAAS SAAS023649 HAMAP MF_00592
Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. SAAS SAAS023649 HAMAP MF_00592
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. SAAS SAAS023649 HAMAP MF_00592
Subcellular location	Cytoplasm By similarity HAMAP MF_00592.
Sequence similarities	Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily. HAMAP MF_00592

Ontologies

Keywords
Cellular component	Cytoplasm SAAS SAAS023649 HAMAP MF_00592
Ligand	Schiff base SAAS SAAS023649 HAMAP MF_00592
Molecular function	Lyase SAAS SAAS023649 HAMAP MF_00592
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	173	1	Schiff-base intermediate with acetaldehyde By similarity HAMAP MF_00592
	Active site	207	1	By similarity HAMAP MF_00592

Sequences

	Sequence		Length	Mass (Da)
	A8ALY0 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: 3187E037CA02C019	FASTA	265	28,346
	10 20 30 40 50 60 MSQENVMTDL TASSLRALKL MDLTTLNDDD TNEKVIALCH QAKTPVGNTA AICIYPRFIP 70 80 90 100 110 120 IARKTLKEQG TPDIRIATVT NFPHGNDDID IALAETRAAI AYGADEVDVV FPYRALIAGN 130 140 150 160 170 180 EQVGFDLVKA CKDACAAANV LLKVIIETGE LKEEALIRKA SEISIKAGAD FIKTSTGKVP 190 200 210 220 230 240 VNATPESARI MMEVIRDMGV SKTVGFKPAG GVRTAEDAQQ FLAIADELFG ADWADSRHYR 250 260 FGASSLLASL LKALGHGDGK SASSY

References

[1]

McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R. Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-895 / CDC 4225-83 / SGSC4696.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000822 Genomic DNA. Translation: ABV14493.1.
RefSeq	YP_001454929.1. NC_009792.1.
3D structure databases
ProteinModelPortal	A8ALY0.
SMR	A8ALY0. Positions 7-257.
ModBase	Search...
Protein-protein interaction databases
STRING	A8ALY0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5580477.
GenomeReviews	Gene locus CKO_03410 in contig CP000822_GR.
KEGG	cko:CKO_03410.
PATRIC	20389374. VBICitKos71230_2865.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0274.
HOGENOM	HBG636421.
OMA	FELVKQC.
ProtClustDB	PRK05283.
Family and domain databases
HAMAP	MF_00592. DeoC_type2. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. IPR023649. DeoC_bac. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01619.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. DeoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A8ALY0_CITK8

Accession

Primary (citable) accession number: A8ALY0

Entry history

Integrated into UniProtKB/TrEMBL:	October 23, 2007
Last sequence update:	October 23, 2007
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)