A8ALC3 (GLND_CITK8) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:	glnD
Ordered Locus Names:	CKO_03202

Organism

Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696) [Complete proteome] [HAMAP]

Taxonomic identifier

290338 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Citrobacter

Protein attributes

Sequence length	890 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein By similarity. HAMAP MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP MF_00277
Sequence similarities	Belongs to the glnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: EC amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 890	890	[Protein-PII] uridylyltransferase HAMAP MF_00277		PRO_1000022338

Sequences

	Sequence		Length	Mass (Da)
	A8ALC3 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: 0B9D5CD45288E395	FASTA	890	102,311
	10 20 30 40 50 60 MNTLPEQHAN TALPTLPGQP QNPGAWSRDE LTVSGIKAHI DIFQQWLGDA FDSGISAEQL 70 80 90 100 110 120 IEARTEFIDQ LLQRLWIDAG FGQIADLALV AVGGYGRGEL HPLSDIDLLI LSRKKLPDAQ 130 140 150 160 170 180 AQKVGELLTL LWDVKLEVGH SVRTLEECLL EGLSDLTVAT NLIETRLLIG DVALFLELQK 190 200 210 220 230 240 HIFSEGFWPS EKFFAAKVEE QNQRHQRYHG TSYNLEPDIK SSPGGLRDIH TLQWVARRHF 250 260 270 280 290 300 GATSLNEMVG FGFLTQAERA ELNECLHILW RIRFALHLVV SRYDNRLLFD RQLSVAQRLN 310 320 330 340 350 360 YTGEGNEPVE HMMKDYFRVT RRVSELNQML LQLFDEAILA LPADEKPRPI DDDFQLRGTL 370 380 390 400 410 420 IDLRDDDLFI RSPEAILRMF YMMVRNSTIT GIYSTTLRHL RHARRHLTQP LCYIPEARSL 430 440 450 460 470 480 FLSMLRHPGA VSRGLLPMHR HSVLWAYMPQ WSHIVGQMQF DLFHAYTVDE HTIRVMLKLE 490 500 510 520 530 540 SFAKEETRQR HPLCVDLWPR LRQPELILIA ALFHDIAKGR GGDHSVLGAQ DVLKFAELHG 550 560 570 580 590 600 LNSRETQLVA WLVRQHLLMS VTAQRRDIQD PEVIKQFAEE VQTEHRLRFL VCLTVADICA 610 620 630 640 650 660 TNETLWNSWK QSLLRELYFA TEKQLRRGMQ NTPDMRERVR HHQLQALALL RMDNINEEAL 670 680 690 700 710 720 HQIWTRCRAN YFVRHSPNQL AWHARHLLQH DLTRPLILVS PQATRGGTEI FIWSPDRPYL 730 740 750 760 770 780 FAAVCAELDR RNLSVHDAQI FTTRDGMAMD TFIVLEPDGS PLSADRHEAI RFGLEQAITQ 790 800 810 820 830 840 SSWQPPQPRR QPAKLRHFTV DTEVTFLPTH TDRKSFLELI ALDQPGLLAR VGQIFADLGI 850 860 870 880 890 SLHGARITTI GERVEDLFII ATADRRALNN ELQQEVHQRL TAALNPNDKG

References

[1]

The Citrobacter koseri Genome Sequencing Project McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R. Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-895 / CDC 4225-83 / SGSC4696.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000822 Genomic DNA. Translation: ABV14286.1.
RefSeq	YP_001454722.1. NC_009792.1.
3D structure databases
ProteinModelPortal	A8ALC3.
ModBase	Search...
Protein-protein interaction databases
STRING	A8ALC3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5583789.
GenomeReviews	Gene locus CKO_03202 in contig CP000822_GR.
KEGG	cko:CKO_03202.
PATRIC	20389000. VBICitKos71230_2678.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HBG687872.
OMA	MQHDLFH.
ProtClustDB	PRK05007.
Family and domain databases
HAMAP	MF_00277. PII_uridylyl-transf. [Tree]
InterPro	IPR002912. ACT-bd. IPR010043. GlnD_Uridyltrans. IPR023279. HD. IPR003607. Metal-dep_PHydrolase_HD_dom. IPR006674. Metal-dep_PHydrolase_HD_sub. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
Gene3D	G3DSA:1.10.3210.10. HD. 1 hit.
KO	K00990.
PANTHER	PTHR13734:SF1. GlnD_Uridyltrans. 1 hit.
Pfam	PF01842. ACT. 2 hits. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_CITK8

Accession

Primary (citable) accession number: A8ALC3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 23, 2007
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program