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A8AL09 (CDH_CITK8) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
CDP-diacylglycerol pyrophosphatase
EC=3.6.1.26
Alternative name(s):
CDP-diacylglycerol phosphatidylhydrolase
CDP-diglyceride hydrolase
Gene names
Name:cdh
Ordered Locus Names:CKO_03081
OrganismCitrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696) [Complete proteome] [HAMAP]
Taxonomic identifier290338 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Citrobacter

Protein attributes

Sequence length249 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

CDP-diacylglycerol + H2O = CMP + phosphatidate. HAMAP MF_00319

Pathway

Phospholipid metabolism; CDP-diacylglycerol degradation; phosphatidate from CDP-diacylglycerol: step 1/1. HAMAP MF_00319

Subcellular location

Cell inner membrane; Single-pass membrane protein By similarity HAMAP MF_00319.

Sequence similarities

Belongs to the cdh family.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   Cellular componentCell inner membrane
Cell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionCDP-diacylglycerol diphosphatase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 249249CDP-diacylglycerol pyrophosphatase HAMAP MF_00319
PRO_1000019262

Regions

Transmembrane7 – 2721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
A8AL09 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: 114B0CAB4D897F5E

FASTA24927,971
        10         20         30         40         50         60 
MKKTGYFLLA VVIVAAVAGI GYWKLAANPN ALRDIVLQQC VPNQLQQQNP APCAEVKPDA 

        70         80         90        100        110        120 
GYVVFKDRNG PLQYLLMPTY RINGTESPLL VEPYTPNFFW LAWQARSFMS QKYGKDIPDS 

       130        140        150        160        170        180 
AISLAINSRS GRTQNHFHIH ISCLRPDVRA QLDDNLAKVS TRWLPLPGGL RGNEYLARRV 

       190        200        210        220        230        240 
TESELAQRSP FMMLAEEVPD AREHMGSYAL AVVRQSDDSF VLLATQRNLL AFNLASAEEI 


QDHQCEILQ

« Hide

References

[1]The Citrobacter koseri Genome Sequencing Project
McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R.
Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-895 / CDC 4225-83 / SGSC4696.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000822 Genomic DNA. Translation: ABV14172.1.
RefSeqYP_001454608.1. NC_009792.1.

3D structure databases

ProteinModelPortalA8AL09.
SMRA8AL09. Positions 30-248.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8AL09.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5584876.
GenomeReviewsGene locus CKO_03081 in contig CP000822_GR.
KEGGcko:CKO_03081.
PATRIC20388790. VBICitKos71230_2578.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2134.
HOGENOMHBG565233.
OMADINGPLQ.
ProtClustDBPRK05471.

Family and domain databases

HAMAPMF_00319. Cdh.
[Tree]
InterProIPR003763. CDP-diacylglyc_Pase.
IPR015993. CDP-diacylglyc_Pase_proteobac.
[Graphical view]
KOK01521.
PfamPF02611. CDH. 1 hit.
[Graphical view]
PIRSFPIRSF001273. CDH. 1 hit.
TIGRFAMsTIGR00672. Cdh. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCDH_CITK8
AccessionPrimary (citable) accession number: A8AL09
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 23, 2007
Last modified: January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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