Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot A8AHD7 (ASTB_CITK8)

Last modified June 16, 2009. Version 9. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Hide | Top

Names and origin

Protein namesRecommended name:
    N-succinylarginine dihydrolase
    EC=3.5.3.23
Gene names
Name: astB
Ordered Locus Names: CKO_01771
OrganismCitrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696) [Complete proteome] [HAMAP]
Taxonomic identifier290338 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Citrobacter

Hide | Top

Protein attributes

Sequence length447 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

Hide | Top

General annotation (Comments)

Function

Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO2 By similarity.

Catalytic activity

N(2)-succinyl-L-arginine + 2 H2O = N(2)-succinyl-L-ornithine + 2 NH3 + CO2. HAMAP MF_01172

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 2/5. HAMAP MF_01172

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the succinylarginine dihydrolase family.

Hide | Top

Ontologies

Keywords
   Biological processArginine metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processarginine catabolic process to glutamate

Inferred from electronic annotation. Source: HAMAP

   Molecular functionN-succinylarginine dihydrolase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Hide | Top

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 447447N-succinylarginine dihydrolase HAMAP MF_01172
PRO_1000065722

Regions

Region19 – 2810Substrate binding By similarity
Region137 – 1382Substrate binding By similarity

Sites

Active site1741 By similarity
Active site2481 By similarity
Active site3651Nucleophile By similarity
Binding site1101Substrate By similarity
Binding site2121Substrate By similarity
Binding site2501Substrate By similarity
Binding site3591Substrate By similarity

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
A8AHD7-1 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: F19A2DF42512AF16

FASTA44749,250
        10         20         30         40         50         60 
MKAHEVNFDG LVGLTHHYAG LSFGNEASIQ HRFQVSNPRL AAKQGLLKMK ALADAGFPQA 

        70         80         90        100        110        120 
VIPPHERPFI PVLRQLGFSG QDEQVLEKVA RQAPHWLSSV SSASPMWVAN AATVCPSADA 

       130        140        150        160        170        180 
LDGKVHLTVA NLNNKFHRAL EAPTTASLLR AIFRDAQFFA VHDALPQVAL LGDEGAANHN 

       190        200        210        220        230        240 
RLGGDYGAPG IQLFVYGREE GVDTRPVRYP ARQTREASEA VARLNQVNPH QVIFARQNPD 

       250        260        270        280        290        300 
VIDLGVFHND VIAVSNRQVL FCHEQAFAKQ GELMRQLRSR VAGFMPLEVP AREVSVQDAV 

       310        320        330        340        350        360 
ATYLFNSQLL SRDDGSMVLV LPQECREHAG VWRYLNALLA ADNPISDLRV FDLRESMANG 

       370        380        390        400        410        420 
GGPACLRLRV VLTEDELRAV NPAVMMNDTL FSTLNDWVDR YYRDRLTAAD LADPQLLREG 

       430        440 
REALDTLTQL LNLGSVYPFQ QEGAGNG

« Hide

Hide | Top

References

[1]McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R.
Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Hide | Top

Cross-references

Sequence databases

CP000822 Genomic DNA. Translation: ABV12900.1.
RefSeqYP_001453336.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID5583623.
GenomeReviewsGene locus CKO_01771 in contig CP000822_GR.
KEGGcko:CKO_01771.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAA8AHD7. HFAHHPA.

Family and domain databases

HAMAPMF_01172.
[Tree]
InterProIPR007079. SuccinylArg_d-Hdrlase_AstB.
[Graphical view]
Gene3DG3DSA:3.75.10.20. SuccinylArg_di_hydro. 1 hit.
PfamPF04996. AstB. 1 hit.
[Graphical view]
TIGRFAMsTIGR03241. arg_catab_astB. 1 hit.
ProtoNetSearch...

Hide | Top

Entry information

Entry nameASTB_CITK8
AccessionPrimary (citable) accession number: A8AHD7
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: October 23, 2007
Last modified: June 16, 2009
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Hide | Top

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents