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Protein

Glutaminase

Gene

glsA

Organism
Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei66SubstrateUniRule annotation1
Binding sitei117SubstrateUniRule annotation1
Binding sitei161SubstrateUniRule annotation1
Binding sitei168SubstrateUniRule annotation1
Binding sitei192SubstrateUniRule annotation1
Binding sitei244SubstrateUniRule annotation1
Binding sitei262Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciCKOS290338:G1G9Z-1366-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:CKO_01543
OrganismiCitrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
Taxonomic identifieri290338 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeCitrobacter
Proteomesi
  • UP000008148 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003360251 – 308GlutaminaseAdd BLAST308

Proteomic databases

PRIDEiA8AGR2

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi290338.CKO_01543

Structurei

3D structure databases

ProteinModelPortaliA8AGR2
SMRiA8AGR2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CSV Bacteria
COG2066 LUCA
HOGENOMiHOG000216890
KOiK01425
OrthoDBiPOG091H02PU

Family and domain databases

HAMAPiMF_00313 Glutaminase, 1 hit
InterProiView protein in InterPro
IPR012338 Beta-lactam/transpept-like
IPR015868 Glutaminase
PANTHERiPTHR12544 PTHR12544, 1 hit
PfamiView protein in Pfam
PF04960 Glutaminase, 1 hit
SUPFAMiSSF56601 SSF56601, 1 hit
TIGRFAMsiTIGR03814 Gln_ase, 1 hit

Sequencei

Sequence statusi: Complete.

A8AGR2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARAMDNSIL ETILQQVRPL IGQGKVADYI PALASVDGSK LGIAICTVDG
60 70 80 90 100
QYYQAGDAQE RFSIQSISKV LSLVVAMRHY PEEEIWQRVG KDPSGSPFNS
110 120 130 140 150
LVQLELEQGI PRNPFINAGA LVVCDMLQGR LSAPRQRMLE VVRALSGVSD
160 170 180 190 200
IAYDVTVARS EFEHSARNAA IAWLMKSFGN FQHDVTTVLQ NYFHYCALKM
210 220 230 240 250
SCAELARTFV FLARQGQAFH LDEPVVTSMQ ARQINALMAT SGMYQNAGEF
260 270 280 290 300
AWRVGLPAKS GVGGGIVAIV PHEMAIAVWS PELDPAGNSL AGIAVLEQLT

QQLGRSVY
Length:308
Mass (Da):33,573
Last modified:May 20, 2008 - v2
Checksum:i7BA455056831DFE3
GO

Sequence cautioni

The sequence ABV12675 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000822 Genomic DNA Translation: ABV12675.1 Different initiation.
RefSeqiWP_024130337.1, NC_009792.1

Genome annotation databases

EnsemblBacteriaiABV12675; ABV12675; CKO_01543
KEGGicko:CKO_01543

Similar proteinsi

Entry informationi

Entry nameiGLSA_CITK8
AccessioniPrimary (citable) accession number: A8AGR2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 20, 2008
Last modified: May 23, 2018
This is version 54 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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