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Protein

Altronate oxidoreductase

Gene

uxaB

Organism
Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-altronate + NAD+ = D-tagaturonate + NADH.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi18 – 29NADUniRule annotationAdd BLAST12

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Enzyme and pathway databases

BioCyciCKOS290338:G1G9Z-1364-MONOMER
UniPathwayiUPA00246

Names & Taxonomyi

Protein namesi
Recommended name:
Altronate oxidoreductaseUniRule annotation (EC:1.1.1.58UniRule annotation)
Alternative name(s):
Tagaturonate dehydrogenaseUniRule annotation
Tagaturonate reductaseUniRule annotation
Gene namesi
Name:uxaBUniRule annotation
Ordered Locus Names:CKO_01541
OrganismiCitrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
Taxonomic identifieri290338 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeCitrobacter
Proteomesi
  • UP000008148 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000447011 – 483Altronate oxidoreductaseAdd BLAST483

Proteomic databases

PRIDEiA8AGR0

Interactioni

Protein-protein interaction databases

STRINGi290338.CKO_01541

Structurei

3D structure databases

ProteinModelPortaliA8AGR0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the mannitol dehydrogenase family. UxaB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QZW Bacteria
COG0246 LUCA
HOGENOMiHOG000029586
KOiK00041
OMAiVVIVRPI
OrthoDBiPOG091H0H06

Family and domain databases

Gene3Di1.10.1040.10, 1 hit
HAMAPiMF_00670 Altron_oxidoreduct, 1 hit
InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR023668 Altronate_OxRdtase
IPR013118 Mannitol_DH_C
IPR013131 Mannitol_DH_N
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF01232 Mannitol_dh, 1 hit
PF08125 Mannitol_dh_C, 1 hit
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 1 hit

Sequencei

Sequence statusi: Complete.

A8AGR0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTLNRRDFP GASYPERIIQ FGEGNFLRAF VDWQVDLLNE HTDLNAGVVI
60 70 80 90 100
VRPIESTFPP SLSTQDGLYT TIIRGLNEKG EAVSDARLIR SVNREISVYD
110 120 130 140 150
NYDEFLKLAH NPDMRFVFSN TTEAGISYHA GDAFDDAPAV SYPAKLTRLL
160 170 180 190 200
FERYTCFDGA LDKGWIIIPC ELIDYNGEAL RELVLRYAQE WNLSAAFVQW
210 220 230 240 250
LDQANTFCST LVDRIVTGYP RDEVTQLEAE LGYHDAFLDT AEHFYLFVIQ
260 270 280 290 300
GPKKVASELR LDKYPLNVLI VDDIKPYKER KVAILNGAHT ALVPVAFQAG
310 320 330 340 350
LDTVGEAMND RDICAFVEKA IYEEIIPVLD LPRDELMSFA SAVTGRFQNP
360 370 380 390 400
YIKHQLLSIA LNGMTKFRTR ILPQLLAGQQ VSGVLPARLT FALAALTAFY
410 420 430 440 450
RGERRGETYP LQDDAHWIER YQQLWHQHSD GLISTQDLVH AVLAVDAHWG
460 470 480
QNLTHVAGLV EQVTTDLDAI LTKGMREAVK PLC
Length:483
Mass (Da):54,486
Last modified:October 23, 2007 - v1
Checksum:i6680F00440B36A51
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000822 Genomic DNA Translation: ABV12673.1
RefSeqiWP_012132414.1, NC_009792.1

Genome annotation databases

EnsemblBacteriaiABV12673; ABV12673; CKO_01541
KEGGicko:CKO_01541

Similar proteinsi

Entry informationi

Entry nameiUXAB_CITK8
AccessioniPrimary (citable) accession number: A8AGR0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 23, 2007
Last modified: May 23, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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