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A8AGR0

- UXAB_CITK8

UniProt

A8AGR0 - UXAB_CITK8

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Protein
Altronate oxidoreductase
Gene
uxaB, CKO_01541
Organism
Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-altronate + NAD+ = D-tagaturonate + NADH.UniRule annotation

Pathwayi

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi18 – 2912NAD By similarity
Add
BLAST

GO - Molecular functioni

  1. coenzyme binding Source: InterPro
  2. tagaturonate reductase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciCKOS290338:GJ8L-1538-MONOMER.
    UniPathwayiUPA00246.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Altronate oxidoreductase (EC:1.1.1.58)
    Alternative name(s):
    Tagaturonate dehydrogenase
    Tagaturonate reductase
    Gene namesi
    Name:uxaB
    Ordered Locus Names:CKO_01541
    OrganismiCitrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
    Taxonomic identifieri290338 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeCitrobacter
    ProteomesiUP000008148: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 483483Altronate oxidoreductaseUniRule annotation
    PRO_1000044701Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi290338.CKO_01541.

    Structurei

    3D structure databases

    ProteinModelPortaliA8AGR0.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0246.
    HOGENOMiHOG000029586.
    KOiK00041.
    OMAiHNTFCST.
    OrthoDBiEOG6CVVB8.

    Family and domain databases

    Gene3Di1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    HAMAPiMF_00670. Altron_oxidoreduct.
    InterProiIPR008927. 6-PGluconate_DH_C-like.
    IPR023668. Altronate_OxRdtase.
    IPR013328. DH_multihelical.
    IPR013118. Mannitol_DH_C.
    IPR013131. Mannitol_DH_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF01232. Mannitol_dh. 1 hit.
    PF08125. Mannitol_dh_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF48179. SSF48179. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A8AGR0-1 [UniParc]FASTAAdd to Basket

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    MKTLNRRDFP GASYPERIIQ FGEGNFLRAF VDWQVDLLNE HTDLNAGVVI    50
    VRPIESTFPP SLSTQDGLYT TIIRGLNEKG EAVSDARLIR SVNREISVYD 100
    NYDEFLKLAH NPDMRFVFSN TTEAGISYHA GDAFDDAPAV SYPAKLTRLL 150
    FERYTCFDGA LDKGWIIIPC ELIDYNGEAL RELVLRYAQE WNLSAAFVQW 200
    LDQANTFCST LVDRIVTGYP RDEVTQLEAE LGYHDAFLDT AEHFYLFVIQ 250
    GPKKVASELR LDKYPLNVLI VDDIKPYKER KVAILNGAHT ALVPVAFQAG 300
    LDTVGEAMND RDICAFVEKA IYEEIIPVLD LPRDELMSFA SAVTGRFQNP 350
    YIKHQLLSIA LNGMTKFRTR ILPQLLAGQQ VSGVLPARLT FALAALTAFY 400
    RGERRGETYP LQDDAHWIER YQQLWHQHSD GLISTQDLVH AVLAVDAHWG 450
    QNLTHVAGLV EQVTTDLDAI LTKGMREAVK PLC 483
    Length:483
    Mass (Da):54,486
    Last modified:October 23, 2007 - v1
    Checksum:i6680F00440B36A51
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000822 Genomic DNA. Translation: ABV12673.1.
    RefSeqiYP_001453109.1. NC_009792.1.

    Genome annotation databases

    EnsemblBacteriaiABV12673; ABV12673; CKO_01541.
    GeneIDi5581390.
    KEGGicko:CKO_01541.
    PATRICi20386163. VBICitKos71230_1299.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000822 Genomic DNA. Translation: ABV12673.1 .
    RefSeqi YP_001453109.1. NC_009792.1.

    3D structure databases

    ProteinModelPortali A8AGR0.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 290338.CKO_01541.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABV12673 ; ABV12673 ; CKO_01541 .
    GeneIDi 5581390.
    KEGGi cko:CKO_01541.
    PATRICi 20386163. VBICitKos71230_1299.

    Phylogenomic databases

    eggNOGi COG0246.
    HOGENOMi HOG000029586.
    KOi K00041.
    OMAi HNTFCST.
    OrthoDBi EOG6CVVB8.

    Enzyme and pathway databases

    UniPathwayi UPA00246 .
    BioCyci CKOS290338:GJ8L-1538-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    HAMAPi MF_00670. Altron_oxidoreduct.
    InterProi IPR008927. 6-PGluconate_DH_C-like.
    IPR023668. Altronate_OxRdtase.
    IPR013328. DH_multihelical.
    IPR013118. Mannitol_DH_C.
    IPR013131. Mannitol_DH_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF01232. Mannitol_dh. 1 hit.
    PF08125. Mannitol_dh_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48179. SSF48179. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-895 / CDC 4225-83 / SGSC4696.

    Entry informationi

    Entry nameiUXAB_CITK8
    AccessioniPrimary (citable) accession number: A8AGR0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: October 23, 2007
    Last modified: May 14, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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