Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A8AGR0 (UXAB_CITK8) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Altronate oxidoreductase

EC=1.1.1.58
Alternative name(s):
Tagaturonate dehydrogenase
Tagaturonate reductase
Gene names
Name:uxaB
Ordered Locus Names:CKO_01541
OrganismCitrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696) [Complete proteome] [HAMAP]
Taxonomic identifier290338 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeCitrobacter

Protein attributes

Sequence length483 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-altronate + NAD+ = D-tagaturonate + NADH. HAMAP-Rule MF_00670

Pathway

Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP-Rule MF_00670

Sequence similarities

Belongs to the mannitol dehydrogenase family. UxaB subfamily.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functioncoenzyme binding

Inferred from electronic annotation. Source: InterPro

tagaturonate reductase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 483483Altronate oxidoreductase HAMAP-Rule MF_00670
PRO_1000044701

Regions

Nucleotide binding18 – 2912NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
A8AGR0 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: 6680F00440B36A51

FASTA48354,486
        10         20         30         40         50         60 
MKTLNRRDFP GASYPERIIQ FGEGNFLRAF VDWQVDLLNE HTDLNAGVVI VRPIESTFPP 

        70         80         90        100        110        120 
SLSTQDGLYT TIIRGLNEKG EAVSDARLIR SVNREISVYD NYDEFLKLAH NPDMRFVFSN 

       130        140        150        160        170        180 
TTEAGISYHA GDAFDDAPAV SYPAKLTRLL FERYTCFDGA LDKGWIIIPC ELIDYNGEAL 

       190        200        210        220        230        240 
RELVLRYAQE WNLSAAFVQW LDQANTFCST LVDRIVTGYP RDEVTQLEAE LGYHDAFLDT 

       250        260        270        280        290        300 
AEHFYLFVIQ GPKKVASELR LDKYPLNVLI VDDIKPYKER KVAILNGAHT ALVPVAFQAG 

       310        320        330        340        350        360 
LDTVGEAMND RDICAFVEKA IYEEIIPVLD LPRDELMSFA SAVTGRFQNP YIKHQLLSIA 

       370        380        390        400        410        420 
LNGMTKFRTR ILPQLLAGQQ VSGVLPARLT FALAALTAFY RGERRGETYP LQDDAHWIER 

       430        440        450        460        470        480 
YQQLWHQHSD GLISTQDLVH AVLAVDAHWG QNLTHVAGLV EQVTTDLDAI LTKGMREAVK 


PLC 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000822 Genomic DNA. Translation: ABV12673.1.
RefSeqYP_001453109.1. NC_009792.1.

3D structure databases

ProteinModelPortalA8AGR0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING290338.CKO_01541.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABV12673; ABV12673; CKO_01541.
GeneID5581390.
KEGGcko:CKO_01541.
PATRIC20386163. VBICitKos71230_1299.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0246.
HOGENOMHOG000029586.
KOK00041.
OMARVIQFGE.
OrthoDBEOG6CVVB8.
ProtClustDBPRK03643.

Enzyme and pathway databases

BioCycCKOS290338:GJ8L-1538-MONOMER.
UniPathwayUPA00246.

Family and domain databases

Gene3D1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPMF_00670. Altron_oxidoreduct.
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR023668. Altronate_OxRdtase.
IPR013328. DH_multihelical.
IPR013118. Mannitol_DH_C.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
SUPFAMSSF48179. SSF48179. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUXAB_CITK8
AccessionPrimary (citable) accession number: A8AGR0
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 23, 2007
Last modified: February 19, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways