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Protein

Cobalt-precorrin-5B C(1)-methyltransferase

Gene

cbiD

Organism
Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.UniRule annotation

Catalytic activityi

Cobalt-precorrin-5B + S-adenosyl-L-methionine = cobalt-precorrin-6A + S-adenosyl-L-homocysteine.UniRule annotation

Pathwayi: adenosylcobalamin biosynthesis

This protein is involved in step 6 of the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route).UniRule annotation
Proteins known to be involved in the 10 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. no protein annotated in this organism
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
  6. Cobalt-precorrin-5B C(1)-methyltransferase (cbiD)
  7. no protein annotated in this organism
  8. no protein annotated in this organism
  9. no protein annotated in this organism
  10. Cobyrinate a,c-diamide synthase (cbiA)
This subpathway is part of the pathway adenosylcobalamin biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route), the pathway adenosylcobalamin biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processCobalamin biosynthesis
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

UniPathwayiUPA00148; UER00227

Names & Taxonomyi

Protein namesi
Recommended name:
Cobalt-precorrin-5B C(1)-methyltransferaseUniRule annotation (EC:2.1.1.195UniRule annotation)
Alternative name(s):
Cobalt-precorrin-6A synthaseUniRule annotation
Gene namesi
Name:cbiDUniRule annotation
Ordered Locus Names:CKO_00806
OrganismiCitrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
Taxonomic identifieri290338 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeCitrobacter
Proteomesi
  • UP000008148 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000468521 – 379Cobalt-precorrin-5B C(1)-methyltransferaseAdd BLAST379

Proteomic databases

PRIDEiA8AEP5

Interactioni

Protein-protein interaction databases

STRINGi290338.CKO_00806

Structurei

3D structure databases

ProteinModelPortaliA8AEP5
SMRiA8AEP5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CbiD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EE8 Bacteria
COG1903 LUCA
HOGENOMiHOG000009126
KOiK02188
OMAiGGIFHTH
OrthoDBiPOG091H02QJ

Family and domain databases

Gene3Di3.30.2110.10, 1 hit
HAMAPiMF_00787 CbiD, 1 hit
InterProiView protein in InterPro
IPR002748 CbiD
IPR036074 CbiD_sf
PANTHERiPTHR35863 PTHR35863, 1 hit
PfamiView protein in Pfam
PF01888 CbiD, 1 hit
PIRSFiPIRSF026782 CbiD, 1 hit
SUPFAMiSSF111342 SSF111342, 1 hit
TIGRFAMsiTIGR00312 cbiD, 1 hit

Sequencei

Sequence statusi: Complete.

A8AEP5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDQSFDAPV WHNGKALRKG YTTGSCATAA AKVAALMVLR QHLIHQVSIV
60 70 80 90 100
TPSGVTLCLN VESPHIEGRQ AIAAIRKDGG DDVDATHGML IFARVTLNDS
110 120 130 140 150
GEITLQGGEG VGTVTRKGIG LPVGSAAINR TPRHTIESVV REAIGPARGA
160 170 180 190 200
DIEIFAPEGE ERAQKTYNAR LGILGGISII GTTGIVTPMS EESWKRSLSL
210 220 230 240 250
ELEIKRAAGL ERVVLVPGNH GERFVREQMG IDTQVVVTMS NFVGYMIEEA
260 270 280 290 300
VRLGYRHIVL IGHPGKLIKI AAGIFHTHSH IADARMETLV AHLALLGAPL
310 320 330 340 350
ELLTRVSDCD TTEAAMEHIE AYGFQHIYNH LAQRICMRVM QMLRFTKTPP
360 370
TCDAIMFSFD NQILGSNRPI EEIVEEMQC
Length:379
Mass (Da):41,211
Last modified:October 23, 2007 - v1
Checksum:iEB8D51AB93E5FC76
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000822 Genomic DNA Translation: ABV11958.1
RefSeqiWP_012131779.1, NC_009792.1

Genome annotation databases

EnsemblBacteriaiABV11958; ABV11958; CKO_00806
KEGGicko:CKO_00806

Similar proteinsi

Entry informationi

Entry nameiCBID_CITK8
AccessioniPrimary (citable) accession number: A8AEP5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 23, 2007
Last modified: May 23, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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