Skip Header

Contribute Send feedback
Read comments (?) or add your own

A8AE07 (MQO_CITK8) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4
Alternative name(s):
MQO
Malate dehydrogenase [quinone]
Gene names
Name:mqo
Ordered Locus Names:CKO_00565
OrganismCitrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696) [Complete proteome] [HAMAP]
Taxonomic identifier290338 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Citrobacter

Protein attributes

Sequence length553 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212

Cofactor

FAD By similarity. HAMAP MF_00212

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212

Sequence similarities

Belongs to the MQO family.

Ontologies

Keywords
   Biological processTricarboxylic acid cycle
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmalate dehydrogenase (menaquinone) activity

Inferred from electronic annotation. Source: EC

malate dehydrogenase (quinone) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 553553Probable malate:quinone oxidoreductase HAMAP MF_00212
PRO_1000023795

Sequences

Sequence LengthMass (Da)Tools
A8AE07 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: F7CB5E240CA2D896

FASTA55360,874
        10         20         30         40         50         60 
MKKVTAMLFT MAVGLNAVSM AAKAKATEEQ ETDVLLIGGG IMSATLGTYL QELEPEWSMT 

        70         80         90        100        110        120 
MVERLDGVAQ ESSNGWNNAG TGHSALMELN YTPKKADGSV SIEKAVDINE AFQVSRQFWA 

       130        140        150        160        170        180 
HQVQSGVLHE PHSFINTVPH MSFVWGDDNV NFLRARYTAL QQSTLFRGMR YSEDHAQIKE 

       190        200        210        220        230        240 
WAPLVMEGRD PKQKVAATRT EIGTDVNYGE ITRQLVASLQ KKPNFALQLN TEVRGFKRNA 

       250        260        270        280        290        300 
DNSWTVTVAD LKNGEAEHAI KAKFVFIGAG GAALKLLQET GIPEAKDYAG FPVGGQFLVS 

       310        320        330        340        350        360 
ENPDVVNNHL AKVYGQASVG APPMSVPHID TRILDGKRVV LFGPFATFST KFLKNGSLWD 

       370        380        390        400        410        420 
LLSSTTTSNF MPMVNVGMDN FDLVKYLISQ VMLSDDERFE ALKEYYPQAK KEDWRLWQAG 

       430        440        450        460        470        480 
QRVQIIKRDE DKGGVLRLGT EVVSDKDGTI AALLGASPGA STAAPIMLHL MEKVFKEKVA 

       490        500        510        520        530        540 
SPEWQAKLKT IVPSYGTKLN GNIEATEQEL QYTSDVLGLK YDKPQVVDEA PKPQLKPQVQ 

       550 
PQPAHKAVAD IAL

« Hide

References

[1]The Citrobacter koseri Genome Sequencing Project
McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R.
Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-895 / CDC 4225-83 / SGSC4696.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000822 Genomic DNA. Translation: ABV11720.1.
RefSeqYP_001452156.1. NC_009792.1.

3D structure databases

ProteinModelPortalA8AE07.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8AE07.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5583834.
GenomeReviewsGene locus CKO_00565 in contig CP000822_GR.
KEGGcko:CKO_00565.
PATRIC20384510. VBICitKos71230_0486.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0579.
HOGENOMHBG289663.
OMAKKWVPLM.
ProtClustDBPRK05257.

Family and domain databases

HAMAPMF_00212. MQO.
[Tree]
InterProIPR006231. Malate_quinone_OxRdtase.
[Graphical view]
KOK00116.
PANTHERPTHR13847:SF14. PTHR13847:SF14. 1 hit.
PfamPF06039. Mqo. 1 hit.
[Graphical view]
TIGRFAMsTIGR01320. Mal_quin_oxido. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMQO_CITK8
AccessionPrimary (citable) accession number: A8AE07
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 23, 2007
Last modified: January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents