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Protein

Adenylate cyclase

Gene

CKO_00148

Organism
Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP = 3',5'-cyclic AMP + diphosphate.UniRule annotation

GO - Molecular functioni

  1. adenylate cyclase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation

Keywords - Biological processi

cAMP biosynthesisUniRule annotation

Enzyme and pathway databases

BioCyciCKOS290338:GJ8L-147-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenylate cyclaseUniRule annotation (EC:4.6.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:CKO_00148Imported
OrganismiCitrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)Imported
Taxonomic identifieri290338 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeCitrobacter
ProteomesiUP000008148 Componenti: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi290338.CKO_00148.

Family & Domainsi

Sequence similaritiesi

Belongs to the adenylyl cyclase class-1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG3072.
HOGENOMiHOG000270910.
KOiK05851.
OMAiPIHGLFL.
OrthoDBiEOG63JR9H.

Family and domain databases

InterProiIPR000274. Adenylate_cyclase_1.
IPR024686. Adenylate_cyclase_1_CS.
IPR024685. Adenylate_cyclase_1_N.
[Graphical view]
PfamiPF12633. Adenyl_cycl_N. 1 hit.
PF01295. Adenylate_cycl. 1 hit.
[Graphical view]
PIRSFiPIRSF001444. Adenylate_cycl. 1 hit.
PROSITEiPS01092. ADENYLATE_CYCLASE_1_1. 1 hit.
PS01093. ADENYLATE_CYCLASE_1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8ACV4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVWLSALAMA IRRMTGSNIR RYVLYLYIET LKQRLDAINQ LRVDRALAAM
60 70 80 90 100
GPAFQQVYSL LPTLLHYHNP LMPGYLDGNV PKGICFYTPD ETQRHYLNEL
110 120 130 140 150
ELYRGMSPQD PPKGELPITG VYSMGSTSSV GQSCSSDLDI WVCHQSWLDS
160 170 180 190 200
EERQLLQRKC SLLESWAASL GVEVSFFLID ENRFRHNESG SLGGEDCGST
210 220 230 240 250
QHILLLDEFY RTAVRLAGKR ILWNMVPCDE EEHYDDYVMT LYAQGVLTPN
260 270 280 290 300
EWLDLGGLSS LSAEEYFGAS LWQLYKSIDS PYKAVLKTLL LEAYSWEYPN
310 320 330 340 350
PRLLAKDIKQ RLHDGEIVSF GLDPYCMMLE RVTEYLTAIE DPTRLDLVRR
360 370 380 390 400
CFYLKVCEKL SRERACVGWR REVLSQLVNE WGWDDARLTM LDNRANWKID
410 420 430 440 450
QVREAHNELL DAMMQSYRNL IRFARRNNLS VSASPQDIGV LTRKLYAAFE
460 470 480 490 500
ALPGKVTLVN PQISPDLSEP NLTFIHVPPG RANRSGWYLY NRAPNMDSII
510 520 530 540 550
SHQPLEYNRY LNKLVAWAWF NGLLTSRTHL FIKGNGIVDL PKLQEMVADV
560 570 580 590 600
SHHFPLRLPA PTPKALYSPC EIRHLAIIVN LEYDPTAAFR NQVVHFDFRK
610 620 630 640 650
LDVFSFGEEQ NCLVGSVDLL YRNSWNEVRT LHFNGEQAMI EALKTILGKM
660 670 680 690 700
HQDAAPPDSV EVFCYSQHLR GLIRTRVQQL VSECIELRLS STRQETGRFK
710 720 730 740 750
ALRVSGQTWG LFFERLNVSV QKLENAIEFY GAISHNKLHG LSVQVETNHV
760 770 780 790 800
KLPSVVDGFA SEGIIQFFFE ETGDEKGFNI YILDESNRAE VYHHCEGSKE
810 820 830 840 850
ELVRDVSRFY SSSHDRFTYG SSFINFNLPQ FYQIVNTDGR EQVIPFRTQP
860 870
ISAVPPANQD NDAPLLQQYF S
Length:871
Mass (Da):100,038
Last modified:October 23, 2007 - v1
Checksum:i206F84BC79DA0BE0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000822 Genomic DNA. Translation: ABV11317.1.
RefSeqiYP_001451753.2. NC_009792.1.

Genome annotation databases

EnsemblBacteriaiABV11317; ABV11317; CKO_00148.
GeneIDi5582139.
KEGGicko:CKO_00148.
PATRICi20383764. VBICitKos71230_0124.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000822 Genomic DNA. Translation: ABV11317.1.
RefSeqiYP_001451753.2. NC_009792.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi290338.CKO_00148.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV11317; ABV11317; CKO_00148.
GeneIDi5582139.
KEGGicko:CKO_00148.
PATRICi20383764. VBICitKos71230_0124.

Phylogenomic databases

eggNOGiCOG3072.
HOGENOMiHOG000270910.
KOiK05851.
OMAiPIHGLFL.
OrthoDBiEOG63JR9H.

Enzyme and pathway databases

BioCyciCKOS290338:GJ8L-147-MONOMER.

Family and domain databases

InterProiIPR000274. Adenylate_cyclase_1.
IPR024686. Adenylate_cyclase_1_CS.
IPR024685. Adenylate_cyclase_1_N.
[Graphical view]
PfamiPF12633. Adenyl_cycl_N. 1 hit.
PF01295. Adenylate_cycl. 1 hit.
[Graphical view]
PIRSFiPIRSF001444. Adenylate_cycl. 1 hit.
PROSITEiPS01092. ADENYLATE_CYCLASE_1_1. 1 hit.
PS01093. ADENYLATE_CYCLASE_1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-895 / CDC 4225-83 / SGSC4696Imported.

Entry informationi

Entry nameiA8ACV4_CITK8
AccessioniPrimary (citable) accession number: A8ACV4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 23, 2007
Last sequence update: October 23, 2007
Last modified: January 7, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.