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A8ACL4 (A8ACL4_CITK8) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chromosomal replication initiator protein DnaA HAMAP MF_00377
Gene names
Name:dnaA HAMAP MF_00377
Ordered Locus Names:CKO_00048
OrganismCitrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696) [Complete proteome] [HAMAP]
Taxonomic identifier290338 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Citrobacter

Protein attributes

Sequence length444 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids By similarity. HAMAP MF_00377 RuleBase RU000577

Subcellular location

Cytoplasm By similarity HAMAP MF_00377.

Sequence similarities

Belongs to the DnaA family. HAMAP MF_00377 RuleBase RU004227

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding149 – 1568ATP By similarity HAMAP MF_00377

Sequences

Sequence LengthMass (Da)Tools
A8ACL4 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: FD5F8FAF5C89D975

FASTA44450,015
        10         20         30         40         50         60 
MWIRPLQAEL SDNTLALYAP NRFVLDWVRD KYLNNINGLL NNFCGADAPQ LRFEVGTKPV 

        70         80         90        100        110        120 
TQTLKTPVNN VVAPAQVAQA QPQRAVPAAA RPGWDNVPAP AEPTYRSNVN VKHTFDNFVE 

       130        140        150        160        170        180 
GKSNQLARAA ARQVADNPGG AYNPLFLYGG TGLGKTHLLH AVGNGIMARK PNAKVVYMHS 

       190        200        210        220        230        240 
ERFVQDMVKA LQNNAIEEFK RYYRSVDALL IDDIQFFANK ERSQEEFFHT FNALLEGNQQ 

       250        260        270        280        290        300 
IILTSDRYPK EINGVEDRLK SRFGWGLTVA IEPPELETRV AILMKKADEN DIRLPGEVAF 

       310        320        330        340        350        360 
FIAKRLRSNV RELEGALNRV IANANFTGRA ITIDFVREAL RDLLALQEKL VTIDNIQKTV 

       370        380        390        400        410        420 
AEYYKIKIAD LLSKRRSRSV ARPRQMAMAL AKELTNHSLP EIGDAFGGRD HTTVLHACRK 

       430        440 
IEQLREESHD IKEDFSNLIR TLSS

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References

[1]McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R.
Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-895 / CDC 4225-83 / SGSC4696.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000822 Genomic DNA. Translation: ABV11227.1.
RefSeqYP_001451663.1. NC_009792.1.

3D structure databases

ProteinModelPortalA8ACL4.
SMRA8ACL4. Positions 351-444.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8ACL4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5583184.
GenomeReviewsGene locus CKO_00048 in contig CP000822_GR.
KEGGcko:CKO_00048.
PATRIC20383582. VBICitKos71230_0043.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0593.
HOGENOMHBG695666.
OMADEVAFLI.

Family and domain databases

HAMAPMF_00377. DnaA_bact.
[Tree]
InterProIPR003593. ATPase_AAA+_core.
IPR001957. Chromosome_initiator_DnaA.
IPR020591. Chromosome_initiator_DnaA-like.
IPR018312. Chromosome_initiator_DnaA_CS.
IPR013159. DnaA_C.
IPR013317. DnaA_Hda.
IPR010921. Trp_repressor/repl_initiator.
[Graphical view]
Gene3DG3DSA:1.10.1750.10. DnaA_C. 1 hit.
KOK02313.
PfamPF00308. Bac_DnaA. 1 hit.
PF08299. Bac_DnaA_C. 1 hit.
[Graphical view]
PRINTSPR00051. DNAA.
SMARTSM00382. AAA. 1 hit.
SM00760. Bac_DnaA_C. 1 hit.
[Graphical view]
SUPFAMSSF48295. Trp_repress_rep. 1 hit.
TIGRFAMsTIGR00362. DnaA. 1 hit.
PROSITEPS01008. DNAA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA8ACL4_CITK8
AccessionPrimary (citable) accession number: A8ACL4
Entry history
Integrated into UniProtKB/TrEMBL: October 23, 2007
Last sequence update: October 23, 2007
Last modified: December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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