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A8ACB5 (A8ACB5_IGNH4) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
NH(3)-dependent NAD(+) synthetase HAMAP MF_00193 RuleBase RU003812
EC=6.3.1.5 HAMAP MF_00193 RuleBase RU003812
Gene names
Name:nadE HAMAP MF_00193
Ordered Locus Names:Igni_1391
OrganismIgnicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125) [Complete proteome] [HAMAP]
Taxonomic identifier453591 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Ignicoccus

Protein attributes

Sequence length275 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+. HAMAP MF_00193 RuleBase RU003812

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (ammonia route): step 1/1. HAMAP MF_00193 RuleBase RU004252

Sequence similarities

Belongs to the NAD synthetase family. HAMAP MF_00193 RuleBase RU003811

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding35 – 428ATP By similarity HAMAP MF_00193

Sites

Active site371 By similarity HAMAP MF_00193

Sequences

Sequence LengthMass (Da)Tools
A8ACB5 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: 872DFA86DE852C2F

FASTA27530,694
        10         20         30         40         50         60 
MRMKLPEPDW DSVRKRIVGW LKDFFQRTGR VAVIGLSGGV DSAVTAALLS EALGPERVRA 

        70         80         90        100        110        120 
LILPSASTPE KDVEDAKRVA RLLGIEDVRV IDVEPALRAF DDLLKVDDRV VRGNTLARIR 

       130        140        150        160        170        180 
MTILYAVAHK DGIVVGTGDK SEFLLGYFTK CGDGCADVFP IGDLYKTWVR KLALHMGLPE 

       190        200        210        220        230        240 
DVALKPSSPR LWPGHLAEEE LGFSYEVADV VLYNLVENGM RPQEIVERLG VDKEIVDRII 

       250        260        270 
QRIKLNKHKL ITPPIVKVTR RTAFEFVEEA DALLT

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000816 Genomic DNA. Translation: ABU82567.1.
RefSeqYP_001435974.1. NC_009776.1.

3D structure databases

ProteinModelPortalA8ACB5.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8ACB5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5561942.
GenomeReviewsGene locus Igni_1391 in contig CP000816_GR.
KEGGiho:Igni_1391.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG08797.
HOGENOMHBG351567.
OMAYDISARD.

Family and domain databases

HAMAPMF_00193. NadE.
[Tree]
InterProIPR022310. NAD/GMP_synthase.
IPR003694. NAD_synthase.
IPR022926. NH(3)-dep_NAD(+)_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
Gene3DG3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KOK01916.
PfamPF02540. NAD_synthase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00552. NadE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA8ACB5_IGNH4
AccessionPrimary (citable) accession number: A8ACB5
Entry history
Integrated into UniProtKB/TrEMBL: October 23, 2007
Last sequence update: October 23, 2007
Last modified: December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info