Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A8AC96 (TF2B_IGNH4) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transcription initiation factor IIB

Short name=TFIIB
Gene names
Name:tfb
Ordered Locus Names:Igni_1372
OrganismIgnicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125) [Complete proteome] [HAMAP]
Taxonomic identifier453591 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeIgnicoccus

Protein attributes

Sequence length316 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB) By similarity. HAMAP-Rule MF_00383

Cofactor

Binds 1 zinc ion per subunit By similarity. HAMAP-Rule MF_00383

Sequence similarities

Belongs to the TFIIB family.

Contains 1 TFIIB-type zinc finger.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 316316Transcription initiation factor IIB HAMAP-Rule MF_00383
PRO_1000080105

Regions

Repeat124 – 207841 HAMAP-Rule MF_00383
Repeat218 – 299822 HAMAP-Rule MF_00383
Zinc finger7 – 3832TFIIB-type HAMAP-Rule MF_00383

Sites

Metal binding111Zinc By similarity
Metal binding141Zinc By similarity
Metal binding301Zinc By similarity
Metal binding331Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
A8AC96 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: D3CF0714EAC2E453

FASTA31636,094
        10         20         30         40         50         60 
MPEQEAFRLR CPVCGSTDIV FNEETGEYVC ARCGTIVLDR YVDQGPEWRA FTPEERERRG 

        70         80         90        100        110        120 
RTGAPLSPTL HDHGLSTVID HRDRDALGKR LSPRKRQEVQ RLRKWQLRAR IQTGMDRNLT 

       130        140        150        160        170        180 
IAMNELDRMA NLLNLPKQIK EEAAVIYRKA VEKGLVRGRS IESVVAAVIY AACRIHHQPR 

       190        200        210        220        230        240 
TLDEIAKKLE VNRKEVARCY RLITKELKLK VPIADAMDHI PRIGEALKLR GDIIEYAMKI 

       250        260        270        280        290        300 
MEKIKGHPIT AGKDPAGIAA AVIYIAVMQK GERRTQKEIA NVAGVTEVTV RNRYKEIMKV 

       310 
LNEMDLEEIE KEVSKK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000816 Genomic DNA. Translation: ABU82548.1.
RefSeqYP_001435955.1. NC_009776.1.

3D structure databases

ProteinModelPortalA8AC96.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING453591.Igni_1372.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABU82548; ABU82548; Igni_1372.
GeneID5562291.
KEGGiho:Igni_1372.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1405.
HOGENOMHOG000108633.
KOK03124.
OMAVLRWRKW.

Enzyme and pathway databases

BioCycIHOS453591:GHYN-1416-MONOMER.

Family and domain databases

Gene3D1.10.472.10. 2 hits.
HAMAPMF_00383. TF2B_arch.
InterProIPR013763. Cyclin-like.
IPR000812. TFIIB.
IPR023484. TFIIB_arc.
IPR023486. TFIIB_CS.
IPR013150. TFIIB_cyclin.
IPR013137. Znf_TFIIB.
[Graphical view]
PANTHERPTHR11618. PTHR11618. 1 hit.
PfamPF08271. TF_Zn_Ribbon. 1 hit.
PF00382. TFIIB. 2 hits.
[Graphical view]
PRINTSPR00685. TIFACTORIIB.
SMARTSM00385. CYCLIN. 2 hits.
[Graphical view]
SUPFAMSSF47954. SSF47954. 2 hits.
PROSITEPS00782. TFIIB. 1 hit.
PS51134. ZF_TFIIB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTF2B_IGNH4
AccessionPrimary (citable) accession number: A8AC96
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: October 23, 2007
Last modified: February 19, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families