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A8AB06 (SYR_IGNH4) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Igni_0928
OrganismIgnicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125) [Complete proteome] [HAMAP]
Taxonomic identifier453591 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeIgnicoccus

Protein attributes

Sequence length622 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 622622Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000018044

Regions

Motif127 – 13711"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A8AB06 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: 8F82B5C7555F1910

FASTA62271,225
        10         20         30         40         50         60 
MYVLSETKSN FLKLIAEALK RRGLEVEEEE LERLAGRPPS PEMGDLGVSL FRYAKKLGLR 

        70         80         90        100        110        120 
PEELTSELKG EIEGRLAGVK EVKAIGGFLN VELEPSWLAE RALREASRED YGKWSFSGRL 

       130        140        150        160        170        180 
VVEHTSANPV HPLHVGHARN MFLGDSLVRI LKNWGADVQS RFYINDMGRQ VAVLVYGLLK 

       190        200        210        220        230        240 
LGRLEPPEGE KPDHWYGKVY SVANALVELN SPSKGDDEKK EWEEVLKELE SKWPEIVREM 

       250        260        270        280        290        300 
KEKFDDEDPE AKVSELMKKY EEGDPEVKET FRKVVNEVLK GFKETMERVG VNVDKWDWES 

       310        320        330        340        350        360 
DLVWSGEVDK IINMAKEKGL VIEKDGALVM VFKNLNDEVR RRLRIPKGLQ IPPLVLKRSD 

       370        380        390        400        410        420 
GTTLYTTRDI AYTIKKFEEF RADRVINVIA AEQRLPQIQL RLALWELGFK EYAENLIHYA 

       430        440        450        460        470        480 
YEMVNVPGMK MSGRRGRMIT LDWLLDEAER RVRELVEGRS EAEDVDEVVK KVAVGAVKFA 

       490        500        510        520        530        540 
MVSVSPEKPI TFKWEEVLNF ERNSAPYLQY TYARAVGILR KGGEPDLERA DYSKAEKYKD 

       550        560        570        580        590        600 
MILSIAEFPE VARKAAEDLK PDLIATYLLS LADKFNEFYH KEPVAKEPDE GLRNLKLALV 

       610        620 
KAVANTIRRG LWLLGVEAPA RM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000816 Genomic DNA. Translation: ABU82108.1.
RefSeqYP_001435515.1. NC_009776.1.

3D structure databases

ProteinModelPortalA8AB06.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING453591.Igni_0928.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABU82108; ABU82108; Igni_0928.
GeneID5562493.
KEGGiho:Igni_0928.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247213.
KOK01887.
OMANFERNSA.

Enzyme and pathway databases

BioCycIHOS453591:GHYN-954-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 2 hits.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSYR_IGNH4
AccessionPrimary (citable) accession number: A8AB06
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 23, 2007
Last modified: May 14, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries