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A8AB02 (A8AB02_IGNH4) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable tRNA pseudouridine synthase B HAMAP-Rule MF_01081
EC=5.4.99.25 HAMAP-Rule MF_01081
Alternative name(s):
tRNA pseudouridine(55) synthase HAMAP-Rule MF_01081
tRNA pseudouridylate synthase HAMAP-Rule MF_01081
tRNA-uridine isomerase HAMAP-Rule MF_01081
Gene names
Name:truB HAMAP-Rule MF_01081
Ordered Locus Names:Igni_0924
OrganismIgnicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125) [Complete proteome] [HAMAP] EMBL ABU82104.1
Taxonomic identifier453591 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Ignicoccus ›

Protein attributes

Sequence length349 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs By similarity. HAMAP-Rule MF_01081

Catalytic activity

tRNA uridine55 = tRNA pseudouridine55. HAMAP-Rule MF_01081

Sequence similarities

Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. HAMAP-Rule MF_01081

Contains 1 PUA domain. HAMAP-Rule MF_01081

Ontologies

Keywords
   Biological processtRNA processing HAMAP-Rule MF_01081
   Molecular functionIsomerase HAMAP-Rule MF_01081
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA pseudouridine synthesis

Inferred from electronic annotation. Source: HAMAP

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: InterPro

pseudouridine synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain254 – 32976PUA By similarity HAMAP-Rule MF_01081

Sites

Active site841Nucleophile By similarity HAMAP-Rule MF_01081

Sequences

Sequence LengthMass (Da)Tools
A8AB02 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: 91F210E09EB6F35F

FASTA34939,643
        10         20         30         40         50         60 
MKEALEWYEE MHRKCDFRGK WVIREEAETD PKYGKEPWKR DVKELVELGV VNLDKPPGPT 

        70         80         90        100        110        120 
SHEVVAWIKR MFGLERAGHG GTLDPKVTGV LPVALAEATK VIHYVMLSGK EYVMVIQFHD 

       130        140        150        160        170        180 
AVKEEEVIEN LKYLVGEIYQ RPPLRSSVKR QLRTKKVYYI HVLEFWPERR MALVRVGSES 

       190        200        210        220        230        240 
GTYMRKLAHD LGLLVGTGAH MRELRRTRSG PFHEDWNLVR MQDLSEAKFL YDNYGDDSLL 

       250        260        270        280        290        300 
KKYIMPCEVA TCHMPKIMIK DGAVDAVAHG ANVSIRGVAA LTDNMKKGDV VAVVSLKGEL 

       310        320        330        340 
VAIAQALVSS QEALKMEKGW VAKTKRVIMK PGTYPDVWRK KKASQQEGG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000816 Genomic DNA. Translation: ABU82104.1.
RefSeqYP_001435511.1. NC_009776.1.

3D structure databases

ProteinModelPortalA8AB02.
ModBaseSearch...

Protein-protein interaction databases

STRING453591.Igni_0924.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABU82104; ABU82104; Igni_0924.
GeneID5562543.
KEGGiho:Igni_0924.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0130.
HOGENOMHOG000231224.
KOK11131.
OMAVDAICHG.

Enzyme and pathway databases

BioCycIHOS453591:GHYN-950-MONOMER.

Family and domain databases

Gene3D2.30.130.10. 1 hit.
HAMAPMF_01081. TruB_arch.
InterProIPR012960. Dyskerin-like.
IPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR002478. PUA.
IPR015947. PUA-like_domain.
IPR004802. tRNA_PsdUridine_synth_B_fam.
IPR026326. TruB_arch.
IPR004521. Uncharacterised_CHP00451.
[Graphical view]
PANTHERPTHR23127. PTHR23127. 1 hit.
PfamPF08068. DKCLD. 1 hit.
PF01472. PUA. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SMARTSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMSSF55120. PsdUridine_synth_cat_dom. 1 hit.
SSF88697. PUA-like. 1 hit.
TIGRFAMsTIGR00425. CBF5. 1 hit.
TIGR00451. unchar_dom_2. 1 hit.
PROSITEPS50890. PUA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA8AB02_IGNH4
AccessionPrimary (citable) accession number: A8AB02
Entry history
Integrated into UniProtKB/TrEMBL: October 23, 2007
Last sequence update: October 23, 2007
Last modified: May 29, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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