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A8AAS3 (A8AAS3_IGNH4) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylaminoimidazole-succinocarboxamide synthase HAMAP MF_00137
EC=6.3.2.6 HAMAP MF_00137
Alternative name(s):
SAICAR synthetase HAMAP MF_00137
Gene names
Name:purC HAMAP MF_00137
Ordered Locus Names:Igni_0843
OrganismIgnicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125) [Complete proteome] [HAMAP]
Taxonomic identifier453591 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Ignicoccus

Protein attributes

Sequence length235 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate. HAMAP MF_00137

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2. HAMAP MF_00137

Sequence similarities

Belongs to the SAICAR synthetase family. HAMAP MF_00137 RuleBase RU004193

Sequences

Sequence LengthMass (Da)Tools
A8AAS3 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: 50532788534D7241

FASTA23526,829
        10         20         30         40         50         60 
MKLIYEGKTK KVYDMDDKVL LKFKDVFTAF DGKKVEEVKG KGKVNAEFTE LLMKYLEQHG 

        70         80         90        100        110        120 
VKTHFLSRNE DEIVAIKTKP LPLEFIVRNY AYGSLLKRLP ILEKGQRLLT PVFEVHYKSD 

       130        140        150        160        170        180 
ELHDPLLAED DPVAAGIVSK DVMKTIRETT LKVNELLTEL FEKAGFKLID FKVEYGITED 

       190        200        210        220        230 
GRVVLIDELS PDSFRAHKGG EAYDKDLFRQ GASGEEVLKK YVELLEALRE ALGVE

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000816 Genomic DNA. Translation: ABU82025.1.
RefSeqYP_001435432.1. NC_009776.1.

3D structure databases

ProteinModelPortalA8AAS3.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8AAS3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5562997.
GenomeReviewsGene locus Igni_0843 in contig CP000816_GR.
KEGGiho:Igni_0843.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG05989.
HOGENOMHBG306070.
OMAYKDDALG.

Family and domain databases

HAMAPMF_00137. SAICAR_synth.
[Tree]
InterProIPR013816. ATP_grasp_subdomain_2.
IPR001636. SAICAR_synth.
IPR018236. SAICAR_synthetase_CS.
[Graphical view]
Gene3DG3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit.
KOK01923.
PANTHERPTHR11609. SAICAR_synt. 1 hit.
PfamPF01259. SAICAR_synt. 1 hit.
[Graphical view]
PROSITEPS01057. SAICAR_SYNTHETASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA8AAS3_IGNH4
AccessionPrimary (citable) accession number: A8AAS3
Entry history
Integrated into UniProtKB/TrEMBL: October 23, 2007
Last sequence update: October 23, 2007
Last modified: November 16, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info