A8AAI6 (KCY_IGNH4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase
Short name=CK
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	Igni_0756

Organism

Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125) [Complete proteome] [HAMAP]

Taxonomic identifier

453591 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Ignicoccus

Protein attributes

Sequence length	172 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00239
Subcellular location	Cytoplasm By similarity HAMAP MF_00239.
Sequence similarities	Belongs to the cytidylate kinase family. Type 2 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro shikimate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 172	172	Cytidylate kinase HAMAP MF_00239		PRO_1000005668
Regions
	Nucleotide binding	8 – 16	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	A8AAI6 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: 0E5DE3F0F284FC4A	FASTA	172	19,113
	10 20 30 40 50 60 MTVVVISGPP GSGKSTVAKK LASELGLRFV SAGSVFRKLA EEIGVSLLEL NEMALKDPEI 70 80 90 100 110 120 DLRIDRMVLE EARRGNVVIE AHLGGWVAAP YADVNVYLTA PLEERAKRIA RRDGISYEEA 130 140 150 160 170 LEEILSREEV QWIRFRKLYG FDVASLEIFD LVVNTALMGP EAVVETIKRM LL

References

[1]

"A genomic analysis of the archaeal system Ignicoccus hospitalis-Nanoarchaeum equitans." Podar M., Anderson I., Makarova K.S., Elkins J.G., Ivanova N., Wall M.A., Lykidis A., Mavromatis K., Sun H., Hudson M.E., Chen W., Deciu C., Hutchison D., Eads J.R., Anderson A., Fernandes F., Szeto E., Lapidus A. , Kyrpides N.C., Saier M.H. Jr., Richardson P.M., Rachel R., Huber H., Eisen J.A., Koonin E.V., Keller M., Stetter K.O. Genome Biol. 9:R158.1-R158.18(2008) [PubMed: 19000309] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KIN4/I / DSM 18386 / JCM 14125.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000816 Genomic DNA. Translation: ABU81938.1.
RefSeq	YP_001435345.1. NC_009776.1.
3D structure databases
ProteinModelPortal	A8AAI6.
ModBase	Search...
Protein-protein interaction databases
STRING	A8AAI6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5561748.
GenomeReviews	Gene locus Igni_0756 in contig CP000816_GR.
KEGG	iho:Igni_0756.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG10101.
HOGENOM	HBG578180.
OMA	CAGFIFR.
ProtClustDB	PRK04182.
Enzyme and pathway databases
BioCyc	IHOS453591:IGNI_0756-MONOMER.
Family and domain databases
HAMAP	MF_00239. Cytidyl_kinase_type2. [Tree]
InterPro	IPR011892. Cyt_kin_arch. IPR000623. Shikimate_kinase. [Graphical view]
KO	K00945.
Pfam	PF01202. SKI. 1 hit. [Graphical view]
PRINTS	PR01100. SHIKIMTKNASE.
TIGRFAMs	TIGR02173. Cyt_kin_arch. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_IGNH4

Accession

Primary (citable) accession number: A8AAI6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 23, 2007
Last modified:	January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program