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A8AA22 (RNP1_IGNH4) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease P protein component 1

Short name=RNase P component 1
EC=3.1.26.5
Alternative name(s):
Rpp29
Gene names
Name:rnp1
Ordered Locus Names:Igni_0592
OrganismIgnicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125) [Complete proteome] [HAMAP]
Taxonomic identifier453591 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeIgnicoccus

Protein attributes

Sequence length92 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00754

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00754

Subunit structure

Consists of a catalytic RNA component and at least 4-5 protein subunits By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00754.

Sequence similarities

Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentCytoplasm
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processmRNA cleavage

Inferred from electronic annotation. Source: InterPro

rRNA processing

Inferred from electronic annotation. Source: InterPro

tRNA 5'-leader removal

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

ribonuclease MRP complex

Inferred from electronic annotation. Source: InterPro

ribonuclease P complex

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: InterPro

ribonuclease P activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 9292Ribonuclease P protein component 1 HAMAP-Rule MF_00754
PRO_1000046611

Sequences

Sequence LengthMass (Da)Tools
A8AA22 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: 7F9921FF8C375C84

FASTA9210,427
        10         20         30         40         50         60 
MKHTPKNVIY HNLVGLRVEV LAHPDPSMKG LKGRIIDESK SFLTIEKDNG ELVKVQKLGT 

        70         80         90 
FVLVLPSGRK VEVRGELLRG RPEERLKKFL KA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000816 Genomic DNA. Translation: ABU81774.1.
RefSeqYP_001435181.1. NC_009776.1.

3D structure databases

ProteinModelPortalA8AA22.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING453591.Igni_0592.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABU81774; ABU81774; Igni_0592.
GeneID5562699.
KEGGiho:Igni_0592.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1588.
HOGENOMHOG000231353.
KOK03538.
OMAQPENRIP.

Enzyme and pathway databases

BioCycIHOS453591:GHYN-612-MONOMER.

Family and domain databases

Gene3D2.30.30.210. 1 hit.
HAMAPMF_00754. RNase_P_1.
InterProIPR002730. RNase_P/MRP_p29.
IPR023538. RNase_P_comp-1.
IPR023534. Rof/RNase_P-like.
[Graphical view]
PfamPF01868. UPF0086. 1 hit.
[Graphical view]
SUPFAMSSF101744. SSF101744. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRNP1_IGNH4
AccessionPrimary (citable) accession number: A8AA22
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 23, 2007
Last modified: July 9, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families