A8AA22 (RNP1_IGNH4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 1
Short name=RNase P component 1
EC=3.1.26.5

Gene names

Name:	rnp1
Ordered Locus Names:	Igni_0592

Organism

Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125) [Complete proteome] [HAMAP]

Taxonomic identifier

453591 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Ignicoccus › Ignicoccus hospitalis

Protein attributes

Sequence length	92 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00754
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00754
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	mRNA cleavage Inferred from electronic annotation. Source: InterPro rRNA processing Inferred from electronic annotation. Source: InterPro tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Cellular_component	ribonuclease MRP complex Inferred from electronic annotation. Source: InterPro ribonuclease P complex Inferred from electronic annotation. Source: InterPro
Molecular_function	RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 92	92	Ribonuclease P protein component 1 HAMAP-Rule MF_00754		PRO_1000046611

Sequences

	Sequence		Length	Mass (Da)
	A8AA22 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: 7F9921FF8C375C84	FASTA	92	10,427
	10 20 30 40 50 60 MKHTPKNVIY HNLVGLRVEV LAHPDPSMKG LKGRIIDESK SFLTIEKDNG ELVKVQKLGT 70 80 90 FVLVLPSGRK VEVRGELLRG RPEERLKKFL KA

References

[1]

"A genomic analysis of the archaeal system Ignicoccus hospitalis-Nanoarchaeum equitans." Podar M., Anderson I., Makarova K.S., Elkins J.G., Ivanova N., Wall M.A., Lykidis A., Mavromatis K., Sun H., Hudson M.E., Chen W., Deciu C., Hutchison D., Eads J.R., Anderson A., Fernandes F., Szeto E., Lapidus A. , Kyrpides N.C., Saier M.H. Jr., Richardson P.M., Rachel R., Huber H., Eisen J.A., Koonin E.V., Keller M., Stetter K.O. Genome Biol. 9:R158.1-R158.18(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KIN4/I / DSM 18386 / JCM 14125.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000816 Genomic DNA. Translation: ABU81774.1.
RefSeq	YP_001435181.1. NC_009776.1.
3D structure databases
ProteinModelPortal	A8AA22.
ModBase	Search...
Protein-protein interaction databases
STRING	453591.Igni_0592.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABU81774; ABU81774; Igni_0592.
GeneID	5562699.
KEGG	iho:Igni_0592.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1588.
HOGENOM	HOG000231353.
KO	K03538.
OMA	IFHELIG.
Enzyme and pathway databases
BioCyc	IHOS453591:GHYN-642-MONOMER.
Family and domain databases
Gene3D	2.30.30.210. 1 hit.
HAMAP	MF_00754. RNase_P_1.
InterPro	IPR002730. RNase_P/MRP_p29. IPR023538. RNase_P_comp-1. IPR023534. Rof/RNase_P-like. [Graphical view]
Pfam	PF01868. UPF0086. 1 hit. [Graphical view]
SUPFAM	SSF101744. RNase_P_Rpp29. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP1_IGNH4

Accession

Primary (citable) accession number: A8AA22

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 23, 2007
Last modified:	May 1, 2013
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program