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A8A9A5 (A8A9A5_IGNH4) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Delta-aminolevulinic acid dehydratase RuleBase RU000515
EC=4.2.1.24 RuleBase RU000515
Gene names
Ordered Locus Names:Igni_0324
OrganismIgnicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125) [Complete proteome] [HAMAP]
Taxonomic identifier453591 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Ignicoccus

Protein attributes

Sequence length342 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 5-aminolevulinate = porphobilinogen + 2 H2O. RuleBase RU000515

Subunit structure

Homooctamer By similarity. PIRSR PIRSR001415-3 RuleBase RU000515

Sequence similarities

Belongs to the ALADH family. RuleBase RU004161

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2051Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Active site2581Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Metal binding1221Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding1241Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding1321Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding2431Magnesium By similarity PIRSR PIRSR001415-5
Binding site2151Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2271Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2851Substrate 2 By similarity PIRSR PIRSR001415-2
Binding site3241Substrate 2 By similarity PIRSR PIRSR001415-2

Sequences

Sequence LengthMass (Da)Tools
A8A9A5 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: 8425DB2959085282

FASTA34238,296
        10         20         30         40         50         60 
MSFPRLRPRR LRKNLYLRDL VAETRLSPRD FIYPIFVKEG IDKPEEISAM PGQMRWPVGE 

        70         80         90        100        110        120 
ELVKHVQEAL DLGVRSVLLF GVPKHKDDLG SSAYDDQGVV QRAVRLLKKE LGDEVVVFTD 

       130        140        150        160        170        180 
VCLCHYTSHG HCGVLAKRCR GDLCEYVVDN DKTLELLAKV ALSHAKAGAD VVAPSSMMDG 

       190        200        210        220        230        240 
MVLAIREALD KEGFTDVAIM SYAAKYASAF YGPFREAASN APQHGDRRTY QMDPRNGEEA 

       250        260        270        280        290        300 
LKEVMLDVKE GADILMVKPA LSYLDVIRRV REAFPHYPLA AYNVSGEYSM VKAAAEKGLV 

       310        320        330        340 
DEKKITLEIL HSIKRAGANI IITYHALEAS RWLKEGLDLK MF

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000816 Genomic DNA. Translation: ABU81507.1.
RefSeqYP_001434914.1. NC_009776.1.

3D structure databases

ProteinModelPortalA8A9A5.
SMRA8A9A5. Positions 5-331.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8A9A5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5563001.
GenomeReviewsGene locus Igni_0324 in contig CP000816_GR.
KEGGiho:Igni_0324.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG05029.
HOGENOMHBG285270.
OMAADLCFCE.
ProtClustDBPRK09283.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR001731. Porphobilinogen_synth.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01698.
PANTHERPTHR11458. AlaD_dehydratase. 1 hit.
PfamPF00490. ALAD. 1 hit.
[Graphical view]
PIRSFPIRSF001415. Porphbilin_synth. 1 hit.
PRINTSPR00144. DALDHYDRTASE.
SMARTSM01004. ALAD. 1 hit.
[Graphical view]
PROSITEPS00169. D_ALA_DEHYDRATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA8A9A5_IGNH4
AccessionPrimary (citable) accession number: A8A9A5
Entry history
Integrated into UniProtKB/TrEMBL: October 23, 2007
Last sequence update: October 23, 2007
Last modified: January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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