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A8A4Q0

- UXAC_ECOHS

UniProt

A8A4Q0 - UXAC_ECOHS

Protein

Uronate isomerase

Gene

uxaC

Organism
Escherichia coli O9:H4 (strain HS)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (23 Oct 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucuronate = D-fructuronate.UniRule annotation
    D-galacturonate = D-tagaturonate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. glucuronate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glucuronate catabolic process Source: InterPro

    Keywords - Molecular functioni

    Isomerase

    Enzyme and pathway databases

    BioCyciECOL331112:GHHI-3268-MONOMER.
    UniPathwayiUPA00246.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
    Alternative name(s):
    Glucuronate isomeraseUniRule annotation
    Uronic isomeraseUniRule annotation
    Gene namesi
    Name:uxaCUniRule annotation
    Ordered Locus Names:EcHS_A3275
    OrganismiEscherichia coli O9:H4 (strain HS)
    Taxonomic identifieri331112 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000001123: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 470470Uronate isomerasePRO_1000061951Add
    BLAST

    Proteomic databases

    PRIDEiA8A4Q0.

    Interactioni

    Protein-protein interaction databases

    STRINGi331112.EcHS_A3275.

    Structurei

    3D structure databases

    ProteinModelPortaliA8A4Q0.
    SMRiA8A4Q0. Positions 4-468.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the uronate isomerase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1904.
    HOGENOMiHOG000224075.
    KOiK01812.
    OMAiARGIMKQ.
    OrthoDBiEOG6J1D95.

    Family and domain databases

    Gene3Di1.10.2020.10. 1 hit.
    HAMAPiMF_00675. UxaC.
    InterProiIPR003766. Uronate_isomerase.
    IPR023177. Uronate_isomerase_dom2.
    [Graphical view]
    PfamiPF02614. UxaC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A8A4Q0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTPFMTEDFL LDTEFARRLY HDYAKDQPIF DYHCHLPPQQ IAEDYRFKNL    50
    YDIWLKGDHY KWRAMRTNGV AERLCTGDAS DREKFDAWAA TVPHTIGNPL 100
    YHWTHLELRR PFGITGKLLS PSTADEIWNE CNELLAQDNF SARGIMQQMN 150
    VKMVGTTDDP IDSLEHHAEI AKDGSFTIKV LPSWRPDKAF NIEQATFNDY 200
    MAKLGEVSDT DIRRFADLQT ALTKRLDHFA AHGCKVSDHA LDVVMFAEAN 250
    EAELDSILAR RLAGETLSEH EVAQFKTAVL VFLGAEYARR GWVQQYHIGA 300
    LRNNNLRQFK LLGPDVGFDS INDRPMAEEL SKLLSKQNEE NLLPKTILYC 350
    LNPRDNEVLG TMIGNFQGEG MPGKMQFGSG WWFNDQKDGM ERQMTQLAQL 400
    GLLSRFVGML TDSRSFLSYT RHEYFRRILC QMIGRWVEAG EAPADINLLG 450
    EMVKNICFNN ARDYFAIELN 470
    Length:470
    Mass (Da):53,987
    Last modified:October 23, 2007 - v1
    Checksum:i9E51AA7B88411281
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000802 Genomic DNA. Translation: ABV07504.1.
    RefSeqiYP_001459887.1. NC_009800.1.

    Genome annotation databases

    EnsemblBacteriaiABV07504; ABV07504; EcHS_A3275.
    GeneIDi5592293.
    KEGGiecx:EcHS_A3275.
    PATRICi18316523. VBIEscCol77814_3199.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000802 Genomic DNA. Translation: ABV07504.1 .
    RefSeqi YP_001459887.1. NC_009800.1.

    3D structure databases

    ProteinModelPortali A8A4Q0.
    SMRi A8A4Q0. Positions 4-468.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 331112.EcHS_A3275.

    Proteomic databases

    PRIDEi A8A4Q0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABV07504 ; ABV07504 ; EcHS_A3275 .
    GeneIDi 5592293.
    KEGGi ecx:EcHS_A3275.
    PATRICi 18316523. VBIEscCol77814_3199.

    Phylogenomic databases

    eggNOGi COG1904.
    HOGENOMi HOG000224075.
    KOi K01812.
    OMAi ARGIMKQ.
    OrthoDBi EOG6J1D95.

    Enzyme and pathway databases

    UniPathwayi UPA00246 .
    BioCyci ECOL331112:GHHI-3268-MONOMER.

    Family and domain databases

    Gene3Di 1.10.2020.10. 1 hit.
    HAMAPi MF_00675. UxaC.
    InterProi IPR003766. Uronate_isomerase.
    IPR023177. Uronate_isomerase_dom2.
    [Graphical view ]
    Pfami PF02614. UxaC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates."
      Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F., Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R., Henderson I.R., Sperandio V., Ravel J.
      J. Bacteriol. 190:6881-6893(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HS.

    Entry informationi

    Entry nameiUXAC_ECOHS
    AccessioniPrimary (citable) accession number: A8A4Q0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 5, 2008
    Last sequence update: October 23, 2007
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3