Reviewed, UniProtKB/Swiss-Prot A8A0V7 (SELD_ECOHS)

Names and origin

Protein names

Recommended name:
    Selenide, water dikinase
    EC=2.7.9.3
Alternative name(s):
    Selenophosphate synthetase
    Selenium donor protein

Gene names

Name:	selD
Ordered Locus Names:	EcHS_A1848

Organism

Escherichia coli O9:H4 (strain HS) [Complete proteome] [HAMAP]

Taxonomic identifier

331112 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	347 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes selenophosphate from selenide and ATP By similarity. HAMAP MF_00625
Catalytic activity	ATP + selenide + H2O = AMP + selenophosphate + phosphate. HAMAP MF_00625
Cofactor	Magnesium By similarity. HAMAP MF_00625
Sequence similarities	Belongs to the selenophosphate synthetase 1 family. Class I subfamily.

Ontologies

Keywords
Ligand	ATP-binding Magnesium Nucleotide-binding Selenium
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP selenide, water dikinase activity Inferred from electronic annotation. Source: HAMAP selenium binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 347	347	Selenide, water dikinase HAMAP MF_00625		PRO_0000318669
Regions
	Nucleotide binding	230 – 236	7	ATP Potential
Sites
	Active site	17	1	Potential
	Site	20	1	Important for catalytic activity By similarity

Sequences

	Sequence		Length	Mass (Da)
	A8A0V7-1 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: 595E5EC9F7B1370F	FASTA	347	36,687
	10 20 30 40 50 60 MSENSIRLTQ YSHGAGCGCK ISPKVLETIL HSEQAKFVDP NLLVGNETRD DAAVYDLGNG 70 80 90 100 110 120 TSVISTTDFF MPIVDNPFDF GRIAATNAIS DIFAMGGKPI MAIAILGWPI NKLSPEIARE 130 140 150 160 170 180 VTEGGRYACR QAGIALAGGH SIDAPEPIFG LAVTGIVPTE RVKKNSTAQA GCKLFLTKPL 190 200 210 220 230 240 GIGVLTTAEK KSLLKPEHQG LATEVMCRMN IAGASFANIE GVKAMTDVTG FGLLGHLSEM 250 260 270 280 290 300 CQGAGVQARV DYEAIPKLPG VEEYIKLGAV PGGTERNFAS YGHLMGEMPR EVRDLLCDPQ 310 320 330 340 TSGGLLLAVM PEAENEVKAT AAEFGIELTA IGELVPARGG RAMVEIR

References

[1]

"The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates." Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F., Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R., Henderson I.R., Sperandio V., Ravel J. J. Bacteriol. 190:6881-6893(2008) [PubMed: 18676672] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000802 Genomic DNA. Translation: ABV06161.1.
RefSeq	YP_001458544.1.
3D structure databases
SMR	A8A0V7. Positions 5-338.
ModBase	Search...
Protein-protein interaction databases
STRING	A8A0V7.
Genome annotation databases
GeneID	5591032.
GenomeReviews	Gene locus EcHS_A1848 in contig CP000802_GR.
KEGG	ecx:EcHS_A1848.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0709.
HOGENOM	HBG383791.
OMA	GGTQRNF.
Family and domain databases
HAMAP	MF_00625. SelD. [Tree]
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR016188. PurM_N-like. IPR004536. SelD. [Graphical view]
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
PIRSF	PIRSF036407. Selenphspht_syn. 1 hit.
TIGRFAMs	TIGR00476. selD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SELD_ECOHS

Accession

Primary (citable) accession number: A8A0V7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	October 23, 2007
Last modified:	February 9, 2010
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)