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Protein
Submitted name:

4-aminobutyrate transaminase

Gene

gabT1

Organism
Escherichia coli O9:H4 (strain HS)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. 4-aminobutyrate transaminase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. gamma-aminobutyric acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciECOL331112:GHHI-1408-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
4-aminobutyrate transaminaseImported (EC:2.6.1.19Imported)
Gene namesi
Name:gabT1Imported
Ordered Locus Names:EcHS_A1417Imported
OrganismiEscherichia coli O9:H4 (strain HS)Imported
Taxonomic identifieri331112 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001123 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi331112.EcHS_A1417.

Structurei

3D structure databases

ProteinModelPortaliA7ZZP4.
SMRiA7ZZP4. Positions 2-421.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0160.
HOGENOMiHOG000020206.
KOiK00823.
OMAiGQRLTNT.
OrthoDBiEOG6QVRHN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7ZZP4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNNEFHQRR LSATPRGVGV MCNFFAQSAE NATLKDVEGN EYIDFAAGIA
60 70 80 90 100
VLNTGHRHPD LVAAVEQQLQ QFTHTAYQIV PYESYVTLAE KINALAPVSG
110 120 130 140 150
QAKTAFFTTG AEAVENAVKM ARAHTGRPGV IAFSGGFHGR TYMTMALTGK
160 170 180 190 200
VAPYKIGFGP FPGSVYHVPY PSDLHGISTQ DSLDAIERLF KSDIEAKQVA
210 220 230 240 250
AIIFEPVQGE GGFNVAPKEL VAAIRRLCDE HGIVMIADEV QSGFARTGKL
260 270 280 290 300
FAMDHYADKP DLMTMAKSLA GGMPLSGVVG NANIMDAPAP GGLGGTYAGN
310 320 330 340 350
PLAVAAAHAV LNIIDKESLC KRANQLGQRL KNTLIDAKES VPAIAAVRGL
360 370 380 390 400
GSMIAAEFND PQTGEPSAAI AQKIQQRALA QGLLLLTCGA YGNVIRFLYP
410 420
LTIPDAQFDA AMKILQDALS D
Length:421
Mass (Da):44,718
Last modified:October 22, 2007 - v1
Checksum:i0300CA23FD8B9D5D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000802 Genomic DNA. Translation: ABV05748.1.
RefSeqiYP_001458131.1. NC_009800.1.

Genome annotation databases

EnsemblBacteriaiABV05748; ABV05748; EcHS_A1417.
GeneIDi5592396.
KEGGiecx:EcHS_A1417.
PATRICi18312816. VBIEscCol77814_1381.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000802 Genomic DNA. Translation: ABV05748.1.
RefSeqiYP_001458131.1. NC_009800.1.

3D structure databases

ProteinModelPortaliA7ZZP4.
SMRiA7ZZP4. Positions 2-421.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi331112.EcHS_A1417.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV05748; ABV05748; EcHS_A1417.
GeneIDi5592396.
KEGGiecx:EcHS_A1417.
PATRICi18312816. VBIEscCol77814_1381.

Phylogenomic databases

eggNOGiCOG0160.
HOGENOMiHOG000020206.
KOiK00823.
OMAiGQRLTNT.
OrthoDBiEOG6QVRHN.

Enzyme and pathway databases

BioCyciECOL331112:GHHI-1408-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates."
    Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F., Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R., Henderson I.R., Sperandio V., Ravel J.
    J. Bacteriol. 190:6881-6893(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HSImported.

Entry informationi

Entry nameiA7ZZP4_ECOHS
AccessioniPrimary (citable) accession number: A7ZZP4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 22, 2007
Last sequence update: October 22, 2007
Last modified: March 31, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.