A7ZXF9 (ALLA_ECOHS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ureidoglycolate hydrolase
EC=3.5.3.19

Gene names

Name:	allA
Ordered Locus Names:	EcHS_A0579

Organism

Escherichia coli O9:H4 (strain HS) [Complete proteome] [HAMAP]

Taxonomic identifier

331112 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	160 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the anaerobic utilization of allantoin. Reinforces the induction of genes involved in the degradation of allantoin and glyoxylate by producing glyoxylate By similarity. HAMAP MF_00616
Catalytic activity	(S)-ureidoglycolate + H2O = glyoxylate + 2 NH3 + CO2. HAMAP MF_00616
Pathway	Nitrogen metabolism; (S)-allantoin degradation; glyoxylate from (S)-ureidoglycolate: step 1/1. HAMAP MF_00616
Subunit structure	Homodimer By similarity. HAMAP MF_00616
Sequence similarities	Belongs to the ureidoglycolate hydrolase family.

Ontologies

Keywords
Biological process	Purine metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	allantoin catabolic process Inferred from electronic annotation. Source: InterPro purine base metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ureidoglycolate hydrolase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 160	160	Ureidoglycolate hydrolase HAMAP MF_00616		PRO_1000061352

Sequences

	Sequence		Length	Mass (Da)
	A7ZXF9 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: E39014610FE93FC6	FASTA	160	18,223
	10 20 30 40 50 60 MKLQVLPLSQ EAFSAYGDVI ETQQRDFFHI NNGLVERYHD LALVEILEQD RTLISINRAQ 70 80 90 100 110 120 PANLPLTIHE LERHPLGTQA FIPMKGEVFV VVVALGDDKP DLSTLRAFIT NGEQGVNYHR 130 140 150 160 NVWHHPLFAW QRVTDFLTID RGGSDNCDVE SIPEQELCFA

References

[1]

"The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates." Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F., Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R., Henderson I.R., Sperandio V., Ravel J. J. Bacteriol. 190:6881-6893(2008) [PubMed: 18676672] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000802 Genomic DNA. Translation: ABV04963.1.
RefSeq	YP_001457346.1. NC_009800.1.
3D structure databases
ProteinModelPortal	A7ZXF9.
SMR	A7ZXF9. Positions 1-160.
ModBase	Search...
Protein-protein interaction databases
STRING	A7ZXF9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000052045; EBESCP00000050030; EBESCG00000051093.
GeneID	5591476.
GenomeReviews	Gene locus EcHS_A0579 in contig CP000802_GR.
KEGG	ecx:EcHS_A0579.
PATRIC	18311144. VBIEscCol77814_0566.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3194.
GeneTree	EBGT00050000010044.
HOGENOM	HBG289179.
OMA	SQAFIPM.
ProtClustDB	PRK03606.
Family and domain databases
HAMAP	MF_00616. Ureidogly_hydro. [Tree]
InterPro	IPR011051. Cupin_RmlC_type. IPR007247. Ureidogly_hydro. IPR023525. Ureidogly_hydro_bac. IPR024060. Ureidoglycolate_hydrolase_dom. [Graphical view]
Gene3D	G3DSA:2.60.120.480. G3DSA:2.60.120.480. 1 hit.
KO	K01483.
PANTHER	PTHR21221. Ureidogly_hydro. 1 hit.
Pfam	PF04115. Ureidogly_hydro. 1 hit. [Graphical view]
PIRSF	PIRSF017306. Ureidogly_hydro. 1 hit.
SUPFAM	SSF51182. RmlC_like_cupin. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALLA_ECOHS

Accession

Primary (citable) accession number: A7ZXF9

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	October 23, 2007
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program