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A7ZSW2

- GLGA_ECO24

UniProt

A7ZSW2 - GLGA_ECO24

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Protein

Glycogen synthase

Gene
glgA, EcE24377A_3908
Organism
Escherichia coli O139:H28 (strain E24377A / ETEC)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucose By similarity

GO - Molecular functioni

  1. starch synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciECOL331111:GH7P-3887-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthase (EC:2.4.1.21)
Alternative name(s):
Starch [bacterial glycogen] synthase
Gene namesi
Name:glgA
Ordered Locus Names:EcE24377A_3908
OrganismiEscherichia coli O139:H28 (strain E24377A / ETEC)
Taxonomic identifieri331111 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001122: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 477477Glycogen synthaseUniRule annotationPRO_1000060430Add
BLAST

Proteomic databases

PRIDEiA7ZSW2.

Interactioni

Protein-protein interaction databases

STRINGi331111.EcE24377A_3908.

Structurei

3D structure databases

ProteinModelPortaliA7ZSW2.
SMRiA7ZSW2. Positions 1-477.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294941.
KOiK00703.
OMAiRYPHCIN.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

A7ZSW2-1 [UniParc]FASTAAdd to Basket

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MQVLHVCSEM FPLLKTGGLA DVIGALPAAQ IADGVDARVL LPAFPDIRRG    50
VTDAQVVSRR DTFAGHITLL FGHYNGVGIY LIDAPHLYDR PGSPYHDTNL 100
FAYTDNVLRF ALLGWVGAEM ASGLDPFWRP DVVHAHDWHA GLAPAYLAAR 150
GRPAKSVFTV HNLAYQGMFY AHHMNDIQLP WSFFNIHGLE FNGQISFLKA 200
GLYYADHITA VSPTYAREIT EPQFAYGMEG LLQQRHREGR LSGVLNGVDE 250
KIWSPETDLL LASRYTRDTL EDKAENKRQL QIAMGLKVDD KVPLFAVVSR 300
LTSQKGLDLV LEALPGLLEQ GGQLALLGAG DPVLQEGFLA AAAEYPGQVG 350
VQIGYHEAFS HRIMGGADVI LVPSRFEPCG LTQLYGLKYG TLPLVRRTGG 400
LADTVSDCSL ENLADGVASG FVFEDSNAWS LLRAIRRAFV LWSRPSLWRF 450
VQRQAMAMDF SWQVAAKSYR ELYYRLK 477
Length:477
Mass (Da):52,822
Last modified:October 23, 2007 - v1
Checksum:i177CF37F8C97CF42
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000800 Genomic DNA. Translation: ABV20730.1.
RefSeqiYP_001464891.1. NC_009801.1.

Genome annotation databases

EnsemblBacteriaiABV20730; ABV20730; EcE24377A_3908.
GeneIDi5588710.
KEGGiecw:EcE24377A_3908.
PATRICi18297088. VBIEscCol31211_4149.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000800 Genomic DNA. Translation: ABV20730.1 .
RefSeqi YP_001464891.1. NC_009801.1.

3D structure databases

ProteinModelPortali A7ZSW2.
SMRi A7ZSW2. Positions 1-477.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 331111.EcE24377A_3908.

Protein family/group databases

CAZyi GT5. Glycosyltransferase Family 5.

Proteomic databases

PRIDEi A7ZSW2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABV20730 ; ABV20730 ; EcE24377A_3908 .
GeneIDi 5588710.
KEGGi ecw:EcE24377A_3908.
PATRICi 18297088. VBIEscCol31211_4149.

Phylogenomic databases

eggNOGi COG0297.
HOGENOMi HOG000294941.
KOi K00703.
OMAi RYPHCIN.
OrthoDBi EOG6JTC6Z.

Enzyme and pathway databases

UniPathwayi UPA00164 .
BioCyci ECOL331111:GH7P-3887-MONOMER.

Family and domain databases

HAMAPi MF_00484. Glycogen_synth.
InterProi IPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view ]
Pfami PF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR02095. glgA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates."
    Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F., Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R., Henderson I.R., Sperandio V., Ravel J.
    J. Bacteriol. 190:6881-6893(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: E24377A / ETEC.

Entry informationi

Entry nameiGLGA_ECO24
AccessioniPrimary (citable) accession number: A7ZSW2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: October 23, 2007
Last modified: May 14, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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