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Protein

Glycerol-3-phosphate dehydrogenase

Gene

glpA

Organism
Escherichia coli O139:H28 (strain E24377A / ETEC)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.UniRule annotation

Cofactori

FADUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Ligandi

FlavoproteinUniRule annotation

Enzyme and pathway databases

BioCyciECOL331111:GH7P-2521-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenaseUniRule annotation (EC:1.1.5.3UniRule annotation)
Gene namesi
Name:glpAImported
Ordered Locus Names:EcE24377A_2539Imported
OrganismiEscherichia coli O139:H28 (strain E24377A / ETEC)Imported
Taxonomic identifieri331111 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001122 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliA7ZP62.
SMRiA7ZP62. Positions 31-365.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0578.
HOGENOMiHOG000004814.
KOiK00111.
OMAiMIAMNHR.
OrthoDBiEOG651SR7.

Family and domain databases

InterProiIPR007419. BFD-like_2Fe2S-bd_dom.
IPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
IPR017752. G3P_DH_GlpA_su.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
PF04324. Fer2_BFD. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
TIGRFAMsiTIGR03377. glycerol3P_GlpA. 1 hit.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7ZP62-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTRDSQSSD VIIIGGGATG AGIARDCALR GLRVILVERH DIATGATGRN
60 70 80 90 100
HGLLHSGARY AVTDAESARE CISENQILKR IARHCVEPTN GLFITLPEDD
110 120 130 140 150
LSFQATFIRA CEEAGISAEA IDPQQARIIE PAVNPALIGA VKVPDGTVDP
160 170 180 190 200
FRLTAANMLD AKEHGAVILT AHEVTGLIRE GATVCGVRVR NHLTGETQAL
210 220 230 240 250
HAPVVVNAAG IWGQHIAEYA DLRIRMFPAK GSLLIMDHRI NQHVINRCRK
260 270 280 290 300
PSDADILVPG DTISLIGTTS LRIDYNEIDD NRVTAEEVDI LLREGEKLAP
310 320 330 340 350
VMAKTRILRA YSGVRPLVAS DDDPSGRNVS RGIVLLDHAE RDGLDGFITI
360 370 380 390 400
TGGKLMTYRL MAEWATDAVC RKLGNTRPCT TADLALPGSQ EPAEVTLRKV
410 420 430 440 450
ISLPAPLRGS AVYRHGDRTP AWLSEGRLHR SLVCECEAVT AGEVQYAVEN
460 470 480 490 500
LNVNSLLDLR RRTRVGMGTC QGELCACRAA GLLQRFNVTT SAQSIEQLST
510 520 530 540
FLNERWKGVQ PIAWGDALRE SEFTRWVYQG LCGLEKEQKD AL
Length:542
Mass (Da):58,958
Last modified:October 23, 2007 - v1
Checksum:iE5C803F89E912E0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000800 Genomic DNA. Translation: ABV16951.1.
RefSeqiWP_000857257.1. NC_009801.1.
YP_001463591.1. NC_009801.1.

Genome annotation databases

EnsemblBacteriaiABV16951; ABV16951; EcE24377A_2539.
KEGGiecw:EcE24377A_2539.
PATRICi18294356. VBIEscCol31211_2820.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000800 Genomic DNA. Translation: ABV16951.1.
RefSeqiWP_000857257.1. NC_009801.1.
YP_001463591.1. NC_009801.1.

3D structure databases

ProteinModelPortaliA7ZP62.
SMRiA7ZP62. Positions 31-365.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV16951; ABV16951; EcE24377A_2539.
KEGGiecw:EcE24377A_2539.
PATRICi18294356. VBIEscCol31211_2820.

Phylogenomic databases

eggNOGiCOG0578.
HOGENOMiHOG000004814.
KOiK00111.
OMAiMIAMNHR.
OrthoDBiEOG651SR7.

Enzyme and pathway databases

BioCyciECOL331111:GH7P-2521-MONOMER.

Family and domain databases

InterProiIPR007419. BFD-like_2Fe2S-bd_dom.
IPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
IPR017752. G3P_DH_GlpA_su.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
PF04324. Fer2_BFD. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
TIGRFAMsiTIGR03377. glycerol3P_GlpA. 1 hit.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates."
    Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F., Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R., Henderson I.R., Sperandio V., Ravel J.
    J. Bacteriol. 190:6881-6893(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: E24377A / ETECImported.

Entry informationi

Entry nameiA7ZP62_ECO24
AccessioniPrimary (citable) accession number: A7ZP62
Entry historyi
Integrated into UniProtKB/TrEMBL: October 23, 2007
Last sequence update: October 23, 2007
Last modified: June 24, 2015
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.