A7ZN77 (MPGP_ECO24) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative mannosyl-3-phosphoglycerate phosphatase
Short name=MPGP
EC=3.1.3.70

Gene names

Ordered Locus Names:

EcE24377A_2188

Organism

Escherichia coli O139:H28 (strain E24377A / ETEC) [Complete proteome] [HAMAP]

Taxonomic identifier

331111 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	271 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2(alpha-D-mannosyl)-3-phosphoglycerate + H2O = 2(alpha-D-mannosyl)-D-glycerate + phosphate. HAMAP MF_00617
Subcellular location	Cytoplasm By similarity HAMAP MF_00617.
Sequence similarities	Belongs to the HAD-like hydrolase superfamily. MPGP family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	mannosyl-3-phosphoglycerate phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 271	271	Putative mannosyl-3-phosphoglycerate phosphatase HAMAP MF_00617		PRO_1000061372

Sequences

	Sequence		Length	Mass (Da)
	A7ZN77 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: 22F094B478EEA0D6	FASTA	271	30,456
	10 20 30 40 50 60 MFSIQQPLLV FSDLDGTLLD SHSYDWQPAA PWLSRLREAN VPVILCSSKT SAEMLYLQKT 70 80 90 100 110 120 LGLQGLPLIA ENGAVIQLAE QWQDIDGFPR IISGISHGEI SQVLNTLREK EHFKFTTFDD 130 140 150 160 170 180 VDDATIAEWT GLSRSQAALT QLHEASVTLI WRDSDERMAQ FTARLNELGL QFMQGARFWH 190 200 210 220 230 240 VLDASAGKDQ AANWIIATYQ QLSGKRPTTL GLGDGPNDAP LLEVMDYAVI VKGLNREGVH 250 260 270 LHDEDPTRVW RTQREGPEGW REGLDHFFSA R

References

[1]

"The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates." Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F., Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R., Henderson I.R., Sperandio V., Ravel J. J. Bacteriol. 190:6881-6893(2008) [PubMed: 18676672] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: E24377A / ETEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000800 Genomic DNA. Translation: ABV20086.1.
RefSeq	YP_001463256.1. NC_009801.1.
3D structure databases
ProteinModelPortal	A7ZN77.
SMR	A7ZN77. Positions 1-234.
ModBase	Search...
Protein-protein interaction databases
STRING	A7ZN77.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000021093; EBESCP00000020155; EBESCG00000020147.
GeneID	5587260.
GenomeReviews	Gene locus EcE24377A_2188 in contig CP000800_GR.
KEGG	ecw:EcE24377A_2188.
PATRIC	18293633. VBIEscCol31211_2466.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3769.
GeneTree	EBGT00050000010795.
HOGENOM	HBG635303.
OMA	LGDSPND.
ProtClustDB	PRK03669.
Enzyme and pathway databases
BioCyc	ECOL331111:ECE24377A_2188-MONOMER.
Family and domain databases
HAMAP	MF_00617. MPGP_rel. [Tree]
InterPro	IPR023214. HAD-like_dom. IPR013200. HAD-SF_hydro-like_3. IPR006379. HAD-SF_hydro_IIB. IPR006381. HAD-SF_hydro_IIB_YedP. IPR012815. MPG_Pase. [Graphical view]
Gene3D	G3DSA:3.40.50.1000. HAD-like_dom. 2 hits.
KO	K07026.
Pfam	PF08282. Hydrolase_3. 1 hit. [Graphical view]
SUPFAM	SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01484. HAD-SF-IIB. 1 hit. TIGR01486. HAD-SF-IIB-MPGP. 1 hit. TIGR02463. MPGP_rel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MPGP_ECO24

Accession

Primary (citable) accession number: A7ZN77

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	October 23, 2007
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program