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A7ZLD0

- A7ZLD0_ECO24

UniProt

A7ZLD0 - A7ZLD0_ECO24

Protein
Submitted name:

4-aminobutyrate transaminase

Gene

gabT1

Organism
Escherichia coli O139:H28 (strain E24377A / ETEC)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (23 Oct 2007)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. 4-aminobutyrate transaminase activity Source: UniProtKB-EC
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. gamma-aminobutyric acid metabolic process Source: InterPro

    Keywords - Molecular functioni

    AminotransferaseImported, Transferase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    BioCyciECOL331111:GH7P-1500-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    4-aminobutyrate transaminaseImported (EC:2.6.1.19Imported)
    Gene namesi
    Name:gabT1Imported
    Ordered Locus Names:EcE24377A_1512Imported
    OrganismiEscherichia coli O139:H28 (strain E24377A / ETEC)Imported
    Taxonomic identifieri331111 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000001122: Chromosome

    PTM / Processingi

    Proteomic databases

    PRIDEiA7ZLD0.

    Interactioni

    Protein-protein interaction databases

    STRINGi331111.EcE24377A_1512.

    Structurei

    3D structure databases

    ProteinModelPortaliA7ZLD0.
    SMRiA7ZLD0. Positions 2-421.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0160.
    HOGENOMiHOG000020206.
    KOiK00823.
    OMAiNIIPYES.
    OrthoDBiEOG6QVRHN.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProiIPR004632. 4NH2But_aminotransferase_bac.
    IPR005814. Aminotrans_3.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view]
    PANTHERiPTHR11986. PTHR11986. 1 hit.
    PfamiPF00202. Aminotran_3. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
    PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A7ZLD0-1 [UniParc]FASTAAdd to Basket

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    MSNNEFHQRR LSATPRGVGV MCNFFAQSAE NATLKDVEGN EYIDFAAGIA    50
    VLNTGHRHPD LVAAVEQQLQ QFTHTAYQIV PYESYVTLAE KINALAPVSG 100
    QAKTAFFTTG AEAVENAVKI ARAHTGRPGV IAFSGGFHGR TYMTMALTGK 150
    VAPYKIGFGP FPGSVYHVPY PSDLHGISTQ DSLDAIERLF KSDIEAKQVA 200
    AIIFEPVQGE GGFNVAPKEL VAAIRRLCDE HGIVMIADEV QSGFARTGKL 250
    FAMDHYADKP DLMTMAKSLA GGMPLSGVVG NANIMDAPAP GGLGGTYAGN 300
    PLAVAAAHAV LNIIDKESLC ERANQLGQRL KNTLIDAKES VPAIAAVRGL 350
    GSMIAVEFND PQTGEPSAAI AQKIQQRALA QGLLLLTCGA YGNVIRFLYP 400
    LTIPDAQFDA AMKILQDALS D 421
    Length:421
    Mass (Da):44,729
    Last modified:October 23, 2007 - v1
    Checksum:iA2C17A885FEBE4EB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000800 Genomic DNA. Translation: ABV18436.1.
    RefSeqiYP_001462609.1. NC_009801.1.

    Genome annotation databases

    EnsemblBacteriaiABV18436; ABV18436; EcE24377A_1512.
    GeneIDi5586616.
    KEGGiecw:EcE24377A_1512.
    PATRICi18292278. VBIEscCol31211_1796.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000800 Genomic DNA. Translation: ABV18436.1 .
    RefSeqi YP_001462609.1. NC_009801.1.

    3D structure databases

    ProteinModelPortali A7ZLD0.
    SMRi A7ZLD0. Positions 2-421.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 331111.EcE24377A_1512.

    Proteomic databases

    PRIDEi A7ZLD0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABV18436 ; ABV18436 ; EcE24377A_1512 .
    GeneIDi 5586616.
    KEGGi ecw:EcE24377A_1512.
    PATRICi 18292278. VBIEscCol31211_1796.

    Phylogenomic databases

    eggNOGi COG0160.
    HOGENOMi HOG000020206.
    KOi K00823.
    OMAi NIIPYES.
    OrthoDBi EOG6QVRHN.

    Enzyme and pathway databases

    BioCyci ECOL331111:GH7P-1500-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProi IPR004632. 4NH2But_aminotransferase_bac.
    IPR005814. Aminotrans_3.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view ]
    PANTHERi PTHR11986. PTHR11986. 1 hit.
    Pfami PF00202. Aminotran_3. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR00700. GABAtrnsam. 1 hit.
    PROSITEi PS00600. AA_TRANSFER_CLASS_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates."
      Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F., Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R., Henderson I.R., Sperandio V., Ravel J.
      J. Bacteriol. 190:6881-6893(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: E24377A / ETECImported.

    Entry informationi

    Entry nameiA7ZLD0_ECO24
    AccessioniPrimary (citable) accession number: A7ZLD0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 23, 2007
    Last sequence update: October 23, 2007
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3