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A7ZK27 (SSUD_ECO24) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alkanesulfonate monooxygenase
EC=1.14.14.5
Alternative name(s):
FMNH2-dependent aliphatic sulfonate monooxygenase
Gene names
Name:ssuD
Ordered Locus Names:EcE24377A_1037
OrganismEscherichia coli O139:H28 (strain E24377A / ETEC) [Complete proteome] [HAMAP]
Taxonomic identifier331111 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length381 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the desulfonation of aliphatic sulfonates By similarity. HAMAP MF_01229

Catalytic activity

An alkanesufonate (R-CH(2)-SO3H) + FMNH2 + O2 = an aldehyde (R-CHO) + FMN + sulfite + H2O. HAMAP MF_01229

Subunit structure

Homotetramer By similarity. HAMAP MF_01229

Miscellaneous

FMNH2 which is absolutely required for this enzymatic reaction, is provided by SsuE By similarity. HAMAP MF_01229

Sequence similarities

Belongs to the SsuD family.

Ontologies

Keywords
   LigandFMN
   Molecular functionMonooxygenase
Oxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionalkanesulfonate monooxygenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 381381Alkanesulfonate monooxygenase HAMAP MF_01229
PRO_1000066819

Sequences

Sequence LengthMass (Da)Tools
A7ZK27 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: 09146AD3B36BE936

FASTA38141,671
        10         20         30         40         50         60 
MSLNMFWFLP THGDGHYLGT EEGSRPVDHG YLQQIAQAAD RLGYTGVLIP TGRSCEDAWL 

        70         80         90        100        110        120 
VAASMIPVTQ RLKFLVALRP SVTSPTVAAR QAATLDRLSN GRALFNLVTG SDPQELAGDG 

       130        140        150        160        170        180 
VFLDHSERYE ASAEFTQVWR RLLLGETVNF NGKHIHVRGA KLLFPPIQQP YPPLYFGGSS 

       190        200        210        220        230        240 
DVAQELAAEQ VDLYLTWGEP PELVKEKIEQ VRAKAAAHGR KIRFGIRLHV IVRETNDEAW 

       250        260        270        280        290        300 
QAAERLISHL DDETIAKAQA AFARTDSVGQ QRMAALHNGK RDNLEISPNL WAGVGLVRGG 

       310        320        330        340        350        360 
AGTALVGDGP TVAARINEYA ALGIDSFVLS GYPHLEEAYR VGELLFPHLD VAIPEIPQPQ 

       370        380 
PLNPQGEAVA NDFIPRKVAQ S

« Hide

References

[1]"The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates."
Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F., Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R., Henderson I.R., Sperandio V., Ravel J.
J. Bacteriol. 190:6881-6893(2008) [PubMed: 18676672] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: E24377A / ETEC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000800 Genomic DNA. Translation: ABV16534.1.
RefSeqYP_001462156.1. NC_009801.1.

3D structure databases

ProteinModelPortalA7ZK27.
SMRA7ZK27. Positions 1-362.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7ZK27.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000022514; EBESCP00000021576; EBESCG00000021568.
GeneID5588937.
GenomeReviewsGene locus EcE24377A_1037 in contig CP000800_GR.
KEGGecw:EcE24377A_1037.
PATRIC18291313. VBIEscCol31211_1323.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2141.
GeneTreeEBGT00050000008394.
HOGENOMHBG639644.
OMASLEGKHI.
ProtClustDBPRK00719.

Enzyme and pathway databases

BioCycECOL331111:ECE24377A_1037-MONOMER.

Family and domain databases

HAMAPMF_01229. Alkanesulf_monooxygen.
[Tree]
InterProIPR019911. Alkanesulphonate_mOase_FMN-dep.
IPR011251. Luciferase-like_dom.
[Graphical view]
Gene3DG3DSA:3.20.20.30. Luciferase_like. 2 hits.
KOK04091.
PfamPF00296. Bac_luciferase. 1 hit.
[Graphical view]
SUPFAMSSF51679. Luciferase_like. 1 hit.
TIGRFAMsTIGR03565. Alk_sulf_monoox. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSSUD_ECO24
AccessionPrimary (citable) accession number: A7ZK27
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: October 23, 2007
Last modified: January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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