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A7ZJZ2

- A7ZJZ2_ECO24

UniProt

A7ZJZ2 - A7ZJZ2_ECO24

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Protein
Submitted name:

Formate acetyltransferase

Gene

pflB2

Organism
Escherichia coli O139:H28 (strain E24377A / ETEC)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei419 – 4191S-acetylcysteine intermediateUniRule annotation
Active sitei420 – 4201Cysteine radical intermediateUniRule annotation

GO - Molecular functioni

  1. formate C-acetyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseImported, Transferase

Enzyme and pathway databases

BioCyciECOL331111:GH7P-993-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Formate acetyltransferaseImported (EC:2.3.1.54Imported)
Gene namesi
Name:pflB2Imported
Ordered Locus Names:EcE24377A_1000Imported
OrganismiEscherichia coli O139:H28 (strain E24377A / ETEC)Imported
Taxonomic identifieri331111 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001122: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei735 – 7351Glycine radicalUniRule annotation

Keywords - PTMi

Organic radicalUniRule annotation

Proteomic databases

PRIDEiA7ZJZ2.

Interactioni

Protein-protein interaction databases

STRINGi331111.EcE24377A_1000.

Structurei

3D structure databases

ProteinModelPortaliA7ZJZ2.
SMRiA7ZJZ2. Positions 2-760.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains glycine radical domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG1882.
HOGENOMiHOG000011346.
KOiK00656.
OMAiHESSIEG.
OrthoDBiEOG6Q8J0J.

Family and domain databases

InterProiIPR005949. Form_AcTrfase.
IPR019777. Form_AcTrfase_GR_CS.
IPR001150. Gly_radical.
IPR004184. PFL_dom.
[Graphical view]
PfamiPF01228. Gly_radical. 1 hit.
PF02901. PFL. 1 hit.
[Graphical view]
PIRSFiPIRSF000379. For_Ac_trans_1. 1 hit.
TIGRFAMsiTIGR01255. pyr_form_ly_1. 1 hit.
PROSITEiPS00850. GLY_RADICAL_1. 1 hit.
PS51149. GLY_RADICAL_2. 1 hit.
PS51554. PFL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7ZJZ2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSELNEKLAT AWEGFTKGDW QNEVNVRDFI QKNYTPYEGD ESFLAGATEA
60 70 80 90 100
TTTLWDKVME GVKLENRTHA PVDFDTAVAS TITSHDAGYI NKQLEKIVGL
110 120 130 140 150
QTEAPLKRAL IPFGGIKMIE GSCKAYNREL DPMIKKIFTE YRKTHNQGVF
160 170 180 190 200
DVYTPDILRC RKSGVLTGLP DAYGRGRIIG DYRRVALYGI DYLMKDKLAQ
210 220 230 240 250
FTSLQADLEN GVNLEQTIRL REEIAEQHRA LGQMKEMAAK YGYDISGPAT
260 270 280 290 300
NAQEAIQWTY FGYLAAVKSQ NGAAMSFGRT STFLDVYIER DLKAGKITEQ
310 320 330 340 350
EAQEMVDHLV MKLRMVRFLR TPEYDELFSG DPIWATESIG GMGLDGRTLV
360 370 380 390 400
TKNSFRFLNT LYTMGPSPEP NMTILWSEKL PLNFKKFAAK VSIDTSSLQY
410 420 430 440 450
ENDDLMRPDF NNDDYAIACC VSPMIVGKQM QFFGARANLA KTMLYAINGG
460 470 480 490 500
VDEKLKMQVG PKSEPIKGDV LNYDEVMERM DHFMDWLAKQ YITALNIIHY
510 520 530 540 550
MHDKYSYEAS LMALHDRDVI RTMACGIAGL SVAADSLSAI KYAKVKPIRD
560 570 580 590 600
EDGLAIDFEI EGEYPQFGNN DPRVDDLAVD LVERFMKKIQ KLHTYRDAIP
610 620 630 640 650
TQSVLTITSN VVYGKKTGNT PDGRRAGAPF GPGANPMHGR DQKGAVASLT
660 670 680 690 700
SVAKLPFAYA KDGISYTFSI VPNALGKDDE VRKTNLAGLM DGYFHHEASI
710 720 730 740 750
EGGQHLNVNV MNREMLLDAM ENPEKYPQLT IRVSGYAVRF NSLTKEQQQD
760
VITRTFTQSM
Length:760
Mass (Da):85,357
Last modified:October 23, 2007 - v1
Checksum:i19323C63081625D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000800 Genomic DNA. Translation: ABV19118.1.
RefSeqiYP_001462121.1. NC_009801.1.

Genome annotation databases

EnsemblBacteriaiABV19118; ABV19118; EcE24377A_1000.
GeneIDi5590867.
KEGGiecw:EcE24377A_1000.
PATRICi18291245. VBIEscCol31211_1289.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000800 Genomic DNA. Translation: ABV19118.1 .
RefSeqi YP_001462121.1. NC_009801.1.

3D structure databases

ProteinModelPortali A7ZJZ2.
SMRi A7ZJZ2. Positions 2-760.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 331111.EcE24377A_1000.

Proteomic databases

PRIDEi A7ZJZ2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABV19118 ; ABV19118 ; EcE24377A_1000 .
GeneIDi 5590867.
KEGGi ecw:EcE24377A_1000.
PATRICi 18291245. VBIEscCol31211_1289.

Phylogenomic databases

eggNOGi COG1882.
HOGENOMi HOG000011346.
KOi K00656.
OMAi HESSIEG.
OrthoDBi EOG6Q8J0J.

Enzyme and pathway databases

BioCyci ECOL331111:GH7P-993-MONOMER.

Family and domain databases

InterProi IPR005949. Form_AcTrfase.
IPR019777. Form_AcTrfase_GR_CS.
IPR001150. Gly_radical.
IPR004184. PFL_dom.
[Graphical view ]
Pfami PF01228. Gly_radical. 1 hit.
PF02901. PFL. 1 hit.
[Graphical view ]
PIRSFi PIRSF000379. For_Ac_trans_1. 1 hit.
TIGRFAMsi TIGR01255. pyr_form_ly_1. 1 hit.
PROSITEi PS00850. GLY_RADICAL_1. 1 hit.
PS51149. GLY_RADICAL_2. 1 hit.
PS51554. PFL. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates."
    Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F., Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R., Henderson I.R., Sperandio V., Ravel J.
    J. Bacteriol. 190:6881-6893(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: E24377A / ETECImported.

Entry informationi

Entry nameiA7ZJZ2_ECO24
AccessioniPrimary (citable) accession number: A7ZJZ2
Entry historyi
Integrated into UniProtKB/TrEMBL: October 23, 2007
Last sequence update: October 23, 2007
Last modified: November 26, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3