Reviewed, UniProtKB/Swiss-Prot A7ZHF4 (ARAB_ECO24)

Names and origin

Protein names

Recommended name:
    Ribulokinase
    EC=2.7.1.16

Gene names

Name:	araB
Ordered Locus Names:	EcE24377A_0065

Organism

Escherichia coli O139:H28 (strain E24377A / ETEC) [Complete proteome] [HAMAP]

Taxonomic identifier

331111 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	566 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate. HAMAP MF_00520
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 2/3. HAMAP MF_00520
Sequence similarities	Belongs to the ribulokinase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	L-arabinose catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ribulokinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 566	566	Ribulokinase HAMAP MF_00520		PRO_1000060917

Sequences

	Sequence		Length	Mass (Da)
	A7ZHF4-1 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: E3EC05ABB06C7237	FASTA	566	61,111
	10 20 30 40 50 60 MAIAIGLDFG SDSVRALAVD CASGEEIATS VEWYPRWQKG QFCDAPNNQF RHHPRDYIES 70 80 90 100 110 120 MEAALKTVLA ELSVEQRAAV VGIGVDTTGS TPAPIDANGN VLALRPEFAE NPNAMFVLWK 130 140 150 160 170 180 DHTAVEEAEE ITRLCHAPGN VDYSRYIGGI YSSEWFWAKI LHVTRQDSAV AQSAASWIEL 190 200 210 220 230 240 CDWVPALLSG TTRPQDIRRG RCSAGHKSLW HESWGGLPPA SFFDELDPIL NRHLPSPLFT 250 260 270 280 290 300 DTWTADIPVG TLCPEWAQRL GLPESVVISG GAFDCHMGAV GAGAQPNALV KVIGTSTCDI 310 320 330 340 350 360 LIADKQSVGE RAVKGICGQV DGSVVPGFIG LEAGQSAFGD IYAWFGRVLG WPLEQLAAQH 370 380 390 400 410 420 PELKAQINAS QKQLLPALTE AWAKNPSLDH LPVVLDWFNG RRTPNANQRL KGVITDLNLA 430 440 450 460 470 480 TDAPLLFGGL IAATAFGARA IMECFTDQGI AVNNVMALGG IARKNQVIMQ ACCDVLNRPL 490 500 510 520 530 540 QIVASDQCCA LGAAIFAAVA AKVHADIPSA QQKMASAVEK TLQPRSEQAQ RFEQLYRRYQ 550 560 QWAMSAEQHY LPTSAPAQAA QAVATL

References

[1]

"The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates." Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F., Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R., Henderson I.R., Sperandio V., Ravel J. J. Bacteriol. 190:6881-6893(2008) [PubMed: 18676672] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000800 Genomic DNA. Translation: ABV20149.1.
RefSeq	YP_001461233.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A7ZHF4.
Genome annotation databases
GeneID	5587106.
GenomeReviews	Gene locus EcE24377A_0065 in contig CP000800_GR.
KEGG	ecw:EcE24377A_0065.
NMPDR	fig|331111.3.peg.2635.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	NGRRTPD.
Family and domain databases
HAMAP	MF_00520. [Tree]
InterPro	IPR000577. Carb_kinase_FGGY. IPR018485. Carb_kinase_FGGY_C. IPR018484. Carb_kinase_FGGY_N. IPR005929. L_ribulokin. [Graphical view]
PANTHER	PTHR10196. FGGY_kin. 1 hit.
Pfam	PF02782. FGGY_C. 1 hit. PF00370. FGGY_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR01234. L-ribulokinase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARAB_ECO24

Accession

Primary (citable) accession number: A7ZHF4

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	October 23, 2007
Last modified:	November 3, 2009
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)