Reviewed, UniProtKB/Swiss-Prot A7ZFS7 (DCD_CAMC1)

Names and origin

Protein names

Recommended name:
    Deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Ccon26_18010
ORF Names:	CCC13826_2308

Organism

Campylobacter concisus (strain 13826) [Complete proteome] [HAMAP]

Taxonomic identifier

360104 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	186 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 186	186	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009698

Sequences

	Sequence		Length	Mass (Da)
	A7ZFS7-1 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: 59126AA153FF2D01	FASTA	186	20,541
	10 20 30 40 50 60 MGLKSDSWIR KMSVEKKMIV PFAEEQVGRG VVSYGVSSYG YDIRVGDEFK IFTNIGGTVV 70 80 90 100 110 120 DPKNFDEKNV VDFKGDVCIV PPNSFALART IEYFNMPDNV LAICLGKSTY ARCGIIVNVT 130 140 150 160 170 180 PFEPGFKGHI TIEISNTTPL PAKIYANEGI AQVLFIEGDE PCEVTYADKN GKYQAQEGIT LPRILK

References

[1]	"Genome sequence of Campylobacter concisus 13826 isolated from human feces." Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., On S., Nelson K.E. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000792 Genomic DNA. Translation: EAT97959.1.
RefSeq	YP_001467635.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A7ZFS7.
Genome annotation databases
GeneID	5596999.
GenomeReviews	Gene locus Ccon26_18010 in contig CP000792_GR.
KEGG	cco:CCC13826_2308.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	CAQVLFF.
Family and domain databases
HAMAP	MF_00146. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. DeoxyUTP_pyroPase_dom. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
ProDom	PD004900. dCTP_deaminase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_CAMC1

Accession

Primary (citable) accession number: A7ZFS7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 23, 2007
Last modified:	November 3, 2009
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)