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A7ZF21 (SYR_CAMC1) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Ccon26_15320
ORF Names:CCC13826_0543
OrganismCampylobacter concisus (strain 13826) [Complete proteome] [HAMAP]
Taxonomic identifier360104 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter

Protein attributes

Sequence length527 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 527527Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000018007

Regions

Motif111 – 12111"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A7ZF21 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: D59CC46E2C8B1465

FASTA52759,455
        10         20         30         40         50         60 
MKDKVKAEIS KVLEREFVLE KPKDKNLAHY ATPLFSLAKE LRKSPAMIAS EFADKFSDSK 

        70         80         90        100        110        120 
IVEASAVNGY LNFKLKSEFL DEISKQILLD SENFAKEDAK KDSYLIEYIS ANPTGPLHIG 

       130        140        150        160        170        180 
HVRGAVYGDT LARLGKRLGY AISTEYYIND AGNQIDLLGT SISLAAKEQL FNESVVYPEK 

       190        200        210        220        230        240 
YYRGDYILDI AKLANEKFGK EIFYDESRNL ELAEFGKDIV LEIIKKDLAD VGIFIESWAS 

       250        260        270        280        290        300 
EKALYDGLEP TINKLKRSNQ MYEKEGATYI ASTTLGDDND RVVVRNDGRP TYLAGDIIYH 

       310        320        330        340        350        360 
NAKFEKNFDH YINIWGADHH GYIARLKAAI NFLGYDENRL EVILMQMVSL LKEGKPYKMS 

       370        380        390        400        410        420 
KRAGNAVLMS DIASEIGAEA LRFIFISKAN TSSLEFDVDE LKKEDSSNPI FYINYAHARI 

       430        440        450        460        470        480 
NQIFAKAGKS VSDVINADFE CLDENSKNLL FEALILPEIL EDAFASRQLQ KIPDYLKSLA 

       490        500        510        520 
ASFHKFYNEN RVVGNENEDS LLKVFAVVAV SIKTAFNIMG ITAKDRM 

« Hide

References

[1]"Genome sequence of Campylobacter concisus 13826 isolated from human feces."
Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., On S., Nelson K.E.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 13826.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000792 Genomic DNA. Translation: EAT99295.1.
RefSeqYP_001467379.1. NC_009802.1.

3D structure databases

ProteinModelPortalA7ZF21.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING360104.CCC13826_0543.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEAT99295; EAT99295; CCC13826_0543.
GeneID5596299.
KEGGcco:CCC13826_0543.
PATRIC20029323. VBICamCon95352_1589.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAPRVKGAI.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycCCON360104:GHAC-1617-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_CAMC1
AccessionPrimary (citable) accession number: A7ZF21
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 23, 2007
Last modified: May 14, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries