Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A7ZEX0

- PNP_CAMC1

UniProt

A7ZEX0 - PNP_CAMC1

Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Campylobacter concisus (strain 13826)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (23 Oct 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

    Catalytic activityi

    RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi515 – 5151MagnesiumUniRule annotation
    Metal bindingi521 – 5211MagnesiumUniRule annotation

    GO - Molecular functioni

    1. 3'-5'-exoribonuclease activity Source: InterPro
    2. magnesium ion binding Source: UniProtKB-HAMAP
    3. polyribonucleotide nucleotidyltransferase activity Source: UniProtKB-HAMAP
    4. RNA binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. mRNA catabolic process Source: UniProtKB-HAMAP
    2. RNA processing Source: InterPro

    Keywords - Molecular functioni

    Nucleotidyltransferase, Transferase

    Keywords - Ligandi

    Magnesium, Metal-binding, RNA-binding

    Enzyme and pathway databases

    BioCyciCCON360104:GHAC-1564-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
    Alternative name(s):
    Polynucleotide phosphorylaseUniRule annotation
    Short name:
    PNPaseUniRule annotation
    Gene namesi
    Name:pnpUniRule annotation
    Ordered Locus Names:Ccon26_14810
    ORF Names:CCC13826_0488
    OrganismiCampylobacter concisus (strain 13826)
    Taxonomic identifieri360104 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
    ProteomesiUP000001121: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 732732Polyribonucleotide nucleotidyltransferasePRO_0000329567Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi360104.CCC13826_0488.

    Structurei

    3D structure databases

    ProteinModelPortaliA7ZEX0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini581 – 64161KHUniRule annotationAdd
    BLAST
    Domaini672 – 73160S1 motifUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation
    Contains 1 KH domain.UniRule annotation
    Contains 1 S1 motif domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1185.
    HOGENOMiHOG000218326.
    KOiK00962.
    OMAiEYIINPD.
    OrthoDBiEOG6WT8CC.

    Family and domain databases

    Gene3Di1.10.10.400. 1 hit.
    2.40.50.140. 1 hit.
    3.30.1370.10. 1 hit.
    3.30.230.70. 2 hits.
    HAMAPiMF_01595. PNPase.
    InterProiIPR001247. ExoRNase_PH_dom1.
    IPR015847. ExoRNase_PH_dom2.
    IPR004087. KH_dom.
    IPR004088. KH_dom_type_1.
    IPR012340. NA-bd_OB-fold.
    IPR012162. PNPase.
    IPR027408. PNPase/RNase_PH_dom.
    IPR015848. PNPase_PH_RNA-bd_bac/org-type.
    IPR003029. Rbsml_prot_S1_RNA-bd_dom.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR022967. RNA-binding_domain_S1.
    [Graphical view]
    PANTHERiPTHR11252. PTHR11252. 1 hit.
    PfamiPF00013. KH_1. 1 hit.
    PF03726. PNPase. 1 hit.
    PF01138. RNase_PH. 2 hits.
    PF03725. RNase_PH_C. 2 hits.
    PF00575. S1. 1 hit.
    [Graphical view]
    PIRSFiPIRSF005499. PNPase. 1 hit.
    SMARTiSM00322. KH. 1 hit.
    SM00316. S1. 1 hit.
    [Graphical view]
    SUPFAMiSSF50249. SSF50249. 1 hit.
    SSF54211. SSF54211. 2 hits.
    SSF54791. SSF54791. 1 hit.
    SSF55666. SSF55666. 2 hits.
    PROSITEiPS50084. KH_TYPE_1. 1 hit.
    PS50126. S1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A7ZEX0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQYSIEVNNQ VEIFDLNKVA KQASGAVLLR VKNTVVLATV AREDVQVEED    50
    FLPLTVQYIE KAYAAGKIPG GYVKRETKPG DFETLTARII DRSLRPLFPK 100
    GYAYPTQIVV MVLSADPEVD LQVVSLNAAS VALYLSDIPV NRPVCGVRVG 150
    YIDDKFVINP SNSELKQSAI DLYVAGTKDE LLMIEMRSLP QQTTQLIPMV 200
    AIEPMIDPSL SDSMAQKQVM NEFSEDKMVE AIDFAGKAIL RASSAYEEAF 250
    KEHKKEDAAL ELKPEIENEN IAIYIDKFYK AEVKNAINQM AKSERASELG 300
    KIAKQISSDE VAQKEGWDEA VITNVLGKYK KKIVREQIIN EGIRADGRGL 350
    EEVRPISIET NVLPNAHGSC LFTRGQTQAL VVATLGTDSD AQMYDILTEK 400
    APLVEKFMFN YNFPGFSVGE ASPLKAPGRR ELGHGNLAKR ALAPSIDLAS 450
    PYTIRVVSEI LESNGSSSMA SVCGGSLALR AAGVNTQKLV AGVAMGLIFE 500
    GEKHAVLTDI MGLEDHDGDM DFKVAGTSDG ITALQMDIKL GGISLEVLKE 550
    ALYQAKRGRE HILALMTQAD KNIEINEDVL PKLELFNVDP SKIVDIIGQA 600
    GKTIKEIIEK FEVSIDLDRE KGEVKIAGGA KKNVDAAKDY IISITSKENS 650
    RSFGKKPFKH DKDRVKPTFN IGDEFTGSVK SVVDFGVFIE LKDGVDGLLH 700
    ISKIKSPLNV GDQVKVCVSE QKGNKISLSL VE 732
    Length:732
    Mass (Da):80,117
    Last modified:October 23, 2007 - v1
    Checksum:i5EFDE418992ACEC5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000792 Genomic DNA. Translation: EAT99186.1.
    RefSeqiWP_012140218.1. NC_009802.1.
    YP_001467328.1. NC_009802.1.

    Genome annotation databases

    EnsemblBacteriaiEAT99186; EAT99186; CCC13826_0488.
    GeneIDi5597076.
    KEGGicco:CCC13826_0488.
    PATRICi20029217. VBICamCon95352_1536.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000792 Genomic DNA. Translation: EAT99186.1 .
    RefSeqi WP_012140218.1. NC_009802.1.
    YP_001467328.1. NC_009802.1.

    3D structure databases

    ProteinModelPortali A7ZEX0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 360104.CCC13826_0488.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai EAT99186 ; EAT99186 ; CCC13826_0488 .
    GeneIDi 5597076.
    KEGGi cco:CCC13826_0488.
    PATRICi 20029217. VBICamCon95352_1536.

    Phylogenomic databases

    eggNOGi COG1185.
    HOGENOMi HOG000218326.
    KOi K00962.
    OMAi EYIINPD.
    OrthoDBi EOG6WT8CC.

    Enzyme and pathway databases

    BioCyci CCON360104:GHAC-1564-MONOMER.

    Family and domain databases

    Gene3Di 1.10.10.400. 1 hit.
    2.40.50.140. 1 hit.
    3.30.1370.10. 1 hit.
    3.30.230.70. 2 hits.
    HAMAPi MF_01595. PNPase.
    InterProi IPR001247. ExoRNase_PH_dom1.
    IPR015847. ExoRNase_PH_dom2.
    IPR004087. KH_dom.
    IPR004088. KH_dom_type_1.
    IPR012340. NA-bd_OB-fold.
    IPR012162. PNPase.
    IPR027408. PNPase/RNase_PH_dom.
    IPR015848. PNPase_PH_RNA-bd_bac/org-type.
    IPR003029. Rbsml_prot_S1_RNA-bd_dom.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR022967. RNA-binding_domain_S1.
    [Graphical view ]
    PANTHERi PTHR11252. PTHR11252. 1 hit.
    Pfami PF00013. KH_1. 1 hit.
    PF03726. PNPase. 1 hit.
    PF01138. RNase_PH. 2 hits.
    PF03725. RNase_PH_C. 2 hits.
    PF00575. S1. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF005499. PNPase. 1 hit.
    SMARTi SM00322. KH. 1 hit.
    SM00316. S1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    SSF54211. SSF54211. 2 hits.
    SSF54791. SSF54791. 1 hit.
    SSF55666. SSF55666. 2 hits.
    PROSITEi PS50084. KH_TYPE_1. 1 hit.
    PS50126. S1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Campylobacter concisus 13826 isolated from human feces."
      Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., On S., Nelson K.E.
      Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 13826.

    Entry informationi

    Entry nameiPNP_CAMC1
    AccessioniPrimary (citable) accession number: A7ZEX0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 29, 2008
    Last sequence update: October 23, 2007
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3