Reviewed, UniProtKB/Swiss-Prot A7ZDP4 (ACKA_CAMC1)

Names and origin

Protein names

Recommended name:
    Acetate kinase
    EC=2.7.2.1
Alternative name(s):
    Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	Ccon26_10400
ORF Names:	CCC13826_0104

Organism

Campylobacter concisus (strain 13826) [Complete proteome] [HAMAP]

Taxonomic identifier

360104 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	397 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 397	397	Acetate kinase HAMAP MF_00020		PRO_1000002213

Sequences

	Sequence		Length	Mass (Da)
	A7ZDP4-1 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: 554D5C639897FE71	FASTA	397	44,206
	10 20 30 40 50 60 MRILVLNSGS SSIKFQLFEM QTKTSLASGL VEQIGSSSSR AVLKANGEIY EIKRFIKDHH 70 80 90 100 110 120 DGLEAMNELF TTSHTLHDLS ELDGIGHRIV HGGESFFSSM IVDESVIKKI EEISPLAPLH 130 140 150 160 170 180 NPGHLAGIKN AMKESKNVPH VVVFDTVFHQ SMPEYAYRYA LPYDVCKTHH IRKYGFHGTS 190 200 210 220 230 240 HRYVCKQAAK MLGIEFDKFN AISLHLGNGA SACAVQNGKS IDTSMGLSPL EGLIMGTRSG 250 260 270 280 290 300 DMDPAVVIYL LNIGVLKWNE IDNFLNKKSG LFGICGSSDM REVVAKMQND ERAKLAFEMF 310 320 330 340 350 360 CYRVKKYIGS YYAILGRVDA LIFTGGIGEN APNTRQKICD DLKHLGIHIN HELNFSNERG 370 380 390 ERCIDEDGAK IKTLIIPTNE ELEIAIETAR VIKERTL

References

[1]	"Genome sequence of Campylobacter concisus 13826 isolated from human feces." Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., On S., Nelson K.E. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000792 Genomic DNA. Translation: EAT97613.1.
RefSeq	YP_001466902.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5597300.
GenomeReviews	Gene locus Ccon26_10400 in contig CP000792_GR.
KEGG	cco:CCC13826_0104.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	A7ZDP4. SLKFAVM.
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate_kin. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_CAMC1

Accession

Primary (citable) accession number: A7ZDP4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 23, 2007
Last modified:	June 16, 2009
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)