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A7ZDP4 (ACKA_CAMC1) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:Ccon26_10400
ORF Names:CCC13826_0104
OrganismCampylobacter concisus (strain 13826) [Complete proteome] [HAMAP]
Taxonomic identifier360104 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length397 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 397397Acetate kinase HAMAP MF_00020
PRO_1000002213

Sequences

Sequence LengthMass (Da)Tools
A7ZDP4 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: 554D5C639897FE71

FASTA39744,206
        10         20         30         40         50         60 
MRILVLNSGS SSIKFQLFEM QTKTSLASGL VEQIGSSSSR AVLKANGEIY EIKRFIKDHH 

        70         80         90        100        110        120 
DGLEAMNELF TTSHTLHDLS ELDGIGHRIV HGGESFFSSM IVDESVIKKI EEISPLAPLH 

       130        140        150        160        170        180 
NPGHLAGIKN AMKESKNVPH VVVFDTVFHQ SMPEYAYRYA LPYDVCKTHH IRKYGFHGTS 

       190        200        210        220        230        240 
HRYVCKQAAK MLGIEFDKFN AISLHLGNGA SACAVQNGKS IDTSMGLSPL EGLIMGTRSG 

       250        260        270        280        290        300 
DMDPAVVIYL LNIGVLKWNE IDNFLNKKSG LFGICGSSDM REVVAKMQND ERAKLAFEMF 

       310        320        330        340        350        360 
CYRVKKYIGS YYAILGRVDA LIFTGGIGEN APNTRQKICD DLKHLGIHIN HELNFSNERG 

       370        380        390 
ERCIDEDGAK IKTLIIPTNE ELEIAIETAR VIKERTL

« Hide

References

[1]"Genome sequence of Campylobacter concisus 13826 isolated from human feces."
Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., On S., Nelson K.E.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 13826.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000792 Genomic DNA. Translation: EAT97613.1.
RefSeqYP_001466902.1. NC_009802.1.

3D structure databases

ProteinModelPortalA7ZDP4.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7ZDP4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5597300.
GenomeReviewsGene locus Ccon26_10400 in contig CP000792_GR.
KEGGcco:CCC13826_0104.
PATRIC20028285. VBICamCon95352_1081.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0282.
HOGENOMHBG285863.
OMADNDARNI.
ProtClustDBPRK00180.

Enzyme and pathway databases

BioCycCCON360104:CCC13826_0104-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_CAMC1
AccessionPrimary (citable) accession number: A7ZDP4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 23, 2007
Last modified: January 25, 2012
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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