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Protein

60 kDa chaperonin

Gene

groL

Organism
Campylobacter concisus (strain 13826)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Ordered Locus Names:Ccon26_07330
ORF Names:CCC13826_0667
OrganismiCampylobacter concisus (strain 13826)
Taxonomic identifieri360104 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000001121 Componenti: Chromosome

Subcellular locationi

A7ZCV2:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000257621 – 54460 kDa chaperoninAdd BLAST544

Proteomic databases

PRIDEiA7ZCV2.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi360104.CCC13826_0667.

Structurei

3D structure databases

ProteinModelPortaliA7ZCV2.
SMRiA7ZCV2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiTDTDKME.
OrthoDBiPOG091H00E7.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

A7ZCV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKEIFYSDD ARNRLYEGVK KLNDAVKVTM GPRGRNVLIQ KSFGAPNITK
60 70 80 90 100
DGVSVAKEVE LKDTIENMGA SLVREVASKT NDQAGDGTTT ATVLAHAIFK
110 120 130 140 150
EGLRNVTAGA NPIEVKRGMD KEVAALIDAL KNISKKVSGS KEIAQIATIS
160 170 180 190 200
ANSDESIGKL IADAMEKVGK DGVITVEEAK SIQDELSVVE GMQFDRGYLS
210 220 230 240 250
PYFITNPEKM QVELSNPFIL LFDKKITNLK DLLPVLEQVQ KSGKPLLIIA
260 270 280 290 300
EDIEGEALAT LVVNKLRGVL NISAVKAPGF GDRRKAMLED IAILTGGEVI
310 320 330 340 350
SEELGRTLES ATINDLGQAS SVVIDKDNTT IVNGAGEKSA IDARITQIKA
360 370 380 390 400
QIAETTSDYD KEKLQERLAK LSGGVAVIKV GAATETEMKE KKDRVDDALS
410 420 430 440 450
ATRAAVEEGI VVGGGSALIL ASKSVNLNLQ GDEAIGAEIV RRALRAPLRQ
460 470 480 490 500
IAENAGFDAG VVANAVETSK DANFGFNAAT GEYVNMFEAG IIDPVKVERV
510 520 530 540
ALQNAVSVAS LLLTTEATIS EIKEEKAMPA MPDMGGMGGM GGMM
Length:544
Mass (Da):57,736
Last modified:October 23, 2007 - v1
Checksum:iAF231F345E8D2BEF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000792 Genomic DNA. Translation: EAT98087.1.
RefSeqiWP_002940160.1. NC_009802.2.

Genome annotation databases

EnsemblBacteriaiEAT98087; EAT98087; CCC13826_0667.
GeneIDi28662856.
KEGGicco:CCC13826_0667.

Similar proteinsi

Entry informationi

Entry nameiCH60_CAMC1
AccessioniPrimary (citable) accession number: A7ZCV2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 23, 2007
Last modified: October 25, 2017
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families