A7ZCE0 (A7ZCE0_CAMC1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL EAT99003.1
EC=2.4.1.182 EMBL EAT99003.1

Gene names

Name:	lpxB EMBL EAT99003.1
Ordered Locus Names:	Ccon26_05550
ORF Names:	CCC13826_1576 EMBL EAT99003.1

Organism

Campylobacter concisus (strain 13826) [Complete proteome] [HAMAP]

Taxonomic identifier

360104 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	344 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 EMBL EAT99003.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A7ZCE0 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: EB5D9F947B1637ED	FASTA	344	38,461
	10 20 30 40 50 60 MKILVSALEP SANLHLKEIL RNFEGEFELM GIFSEELGTP YMKSSEFSAM GFVEVLPLIF 70 80 90 100 110 120 KAKKAMKAMS QMAKEADAVL LIDSPAFNLP LAKAIKAAGA KAAVTYYILP QVWAWKPKRV 130 140 150 160 170 180 SAVERYCDNL ASILPFDAKF YSRSTYVGHP LMDEIKLKKT SLSSSGKVAF LPGSRRSEIS 190 200 210 220 230 240 RLMPVYRELA KKIDAKRLLV VPPFLLDKMD EIYGDTSDFE IVSNTPEALY ESDFAFVCSG 250 260 270 280 290 300 TATLEAALIG TPFVLAYKAK AIDVFIARKF VKIKHAGLAN IMFDFMGKEP LHEEFIQEFA 310 320 330 340 TAENLLRAYK SCDRQKFLKG CDELRAYLGH GSSKNVVKIL KNME

References

[1]	"Genome sequence of Campylobacter concisus 13826 isolated from human feces." Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., On S., Nelson K.E. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000792 Genomic DNA. Translation: EAT99003.1.
RefSeq	YP_001466448.1. NC_009802.1.
3D structure databases
ProteinModelPortal	A7ZCE0.
ModBase	Search...
Protein-protein interaction databases
STRING	A7ZCE0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5595656.
GenomeReviews	Gene locus Ccon26_05550 in contig CP000792_GR.
KEGG	cco:CCC13826_1576.
PATRIC	20027267. VBICamCon95352_0588.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0763.
HOGENOM	HBG584837.
OMA	HEEFIQE.
ProtClustDB	PRK14089.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A7ZCE0_CAMC1

Accession

Primary (citable) accession number: A7ZCE0

Entry history

Integrated into UniProtKB/TrEMBL:	October 23, 2007
Last sequence update:	October 23, 2007
Last modified:	December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)