SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A7ZC69

- IF2_CAMC1

UniProt

A7ZC69 - IF2_CAMC1

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Translation initiation factor IF-2
Gene
infB, Ccon26_04760, CCC13826_1495
Organism
Campylobacter concisus (strain 13826)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi393 – 4008GTP By similarity
Nucleotide bindingi439 – 4435GTP By similarity
Nucleotide bindingi493 – 4964GTP By similarity

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-KW
  2. GTPase activity Source: UniProtKB-HAMAP
  3. translation initiation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCCON360104:GHAC-504-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-2
Gene namesi
Name:infB
Ordered Locus Names:Ccon26_04760
ORF Names:CCC13826_1495
OrganismiCampylobacter concisus (strain 13826)
Taxonomic identifieri360104 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
ProteomesiUP000001121: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 885885Translation initiation factor IF-2UniRule annotation
PRO_1000008219Add
BLAST

Proteomic databases

PRIDEiA7ZC69.

Interactioni

Protein-protein interaction databases

STRINGi360104.CCC13826_1495.

Structurei

3D structure databases

ProteinModelPortaliA7ZC69.
SMRiA7ZC69. Positions 788-876.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini384 – 553170tr-type G
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni393 – 4008G1 By similarity
Regioni418 – 4225G2 By similarity
Regioni439 – 4424G3 By similarity
Regioni493 – 4964G4 By similarity
Regioni529 – 5313G5 By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0532.
HOGENOMiHOG000076906.
KOiK02519.
OMAiEHEFIPV.
OrthoDBiEOG67HJSV.

Family and domain databases

Gene3Di3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00100_B. IF_2_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 2 hits.
PF11987. IF-2. 1 hit.
PF04760. IF2_N. 2 hits.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7ZC69-1 [UniParc]FASTAAdd to Basket

« Hide

MSNVRISEIA NELGYPSKEI VEKAQELGLK VKTHSNAVSL EEAEAIYEYV    50
QTGVIPDKFK KKKSEPKAKK EPKKETEKEP AKKEEKPKTE PKKAATKAEP 100
KPEKAKAEPK KEAQISEEKP KTEPKKEEPV KVEQKPAEAP KPKESLADVT 150
QKRRGLVIVK KKKDYEAPAP IKEEKKAEAA VTNISDFKSM FSASDENLAR 200
KKKKEKKVTV VSKKDSAEKM DLLGGSDFGD IVLEDEDVVV LPDFSFKTPA 250
PTPMQRTKQP NAMKTTVNNT INSFGEGGIQ RRARKKHKKP ENKQNSEAVT 300
SINIPKEIRV YEFAEKLNKQ PSEVIGKLFM LGMMTTKNDF LDEDAIEILA 350
DEFNVEVNII DDQKEFDYVA AYEEEIKDDE NLQPRAPVIT IMGHVDHGKT 400
SLLDYIRKSR VAAGEAGGIT QHVGAYMVNK NGRNITFIDT PGHEAFTAMR 450
ARGAGVTDIV IIVVAADDGV KPQTKEAVSH AKAAGVPIII AINKMDKESA 500
NPDLVKTGLA ELDIMPTEWG GKYEFVPISA KTGMGIDDLL EIVLLQADLL 550
ELKANPKANA KATVIESSLQ KGRGPVATII VENGTLHVGD TVVAGVAYGK 600
IRSLLDDQGR SLREIKPGEC GVIVGLSEIA EAGETLIGVK TDKEAREYAQ 650
KKAEYIRQKE LSKSTKVSID ELSAKIAEGE LKTLPVIIKA DVGGSLEALK 700
ASLEKLANDE IRVNVIHSGV GGITQSDVAL ASASNDCIIL GFNIRPTGEI 750
KEKAKESGVE IKTYNVIYNL IDDVKAILGG LMSPIIREEQ LGQAQVRQVI 800
HVPKVGTIAG CIVTEGTINR GAKIRLIREG VVVYEGLVSS LKRFKDDVKE 850
VAKGYECGVG IENFNDIREN DYIESFKEVK EKATL 885
Length:885
Mass (Da):96,941
Last modified:October 23, 2007 - v1
Checksum:i8A1AADE7F6978261
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000792 Genomic DNA. Translation: EAT99040.1.
RefSeqiYP_001466377.1. NC_009802.1.

Genome annotation databases

EnsemblBacteriaiEAT99040; EAT99040; CCC13826_1495.
GeneIDi5597328.
KEGGicco:CCC13826_1495.
PATRICi20027103. VBICamCon95352_0507.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000792 Genomic DNA. Translation: EAT99040.1 .
RefSeqi YP_001466377.1. NC_009802.1.

3D structure databases

ProteinModelPortali A7ZC69.
SMRi A7ZC69. Positions 788-876.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 360104.CCC13826_1495.

Proteomic databases

PRIDEi A7ZC69.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai EAT99040 ; EAT99040 ; CCC13826_1495 .
GeneIDi 5597328.
KEGGi cco:CCC13826_1495.
PATRICi 20027103. VBICamCon95352_0507.

Phylogenomic databases

eggNOGi COG0532.
HOGENOMi HOG000076906.
KOi K02519.
OMAi EHEFIPV.
OrthoDBi EOG67HJSV.

Enzyme and pathway databases

BioCyci CCON360104:GHAC-504-MONOMER.

Family and domain databases

Gene3Di 3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00100_B. IF_2_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view ]
PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 2 hits.
PF11987. IF-2. 1 hit.
PF04760. IF2_N. 2 hits.
[Graphical view ]
SUPFAMi SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Campylobacter concisus 13826 isolated from human feces."
    Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., On S., Nelson K.E.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 13826.

Entry informationi

Entry nameiIF2_CAMC1
AccessioniPrimary (citable) accession number: A7ZC69
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 23, 2007
Last modified: September 3, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi