A7ZB08 (GLMM_CAMC1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Ccon26_00450
ORF Names:	CCC13826_1807

Organism

Campylobacter concisus (strain 13826) [Complete proteome] [HAMAP]

Taxonomic identifier

360104 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	446 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 446	446	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_1000073570
Sites
	Active site	99	1	Phosphoserine intermediate By similarity
	Metal binding	99	1	Magnesium; via phosphate group By similarity
	Metal binding	242	1	Magnesium By similarity
	Metal binding	244	1	Magnesium By similarity
	Metal binding	246	1	Magnesium By similarity
Amino acid modifications
	Modified residue	99	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A7ZB08 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: 679CD710DDC60D0B	FASTA	446	48,781
	10 20 30 40 50 60 MKLFGTDGVR GKAGEKLSAQ TSMRLAMAAG IYFRKTSATN VILVGKDTRK SGYMIETAIV 70 80 90 100 110 120 AGLTAVGYNV LQIGPMPTPA IAFLTENMRC DAGIMISASH NPYYDNGIKF FDSFGNKLDE 130 140 150 160 170 180 TIEAEIEKIF YDDELIANAQ KTMTEIGANK RIDDVIGRYI VQIKNSFPKE LNLKNLRVVL 190 200 210 220 230 240 DVANGAAYKV APTVFSELGA DVIVINNEPN GSNINQNCGA LHPEDLASEV KRLRADIGFA 250 260 270 280 290 300 FDGDADRLVV VDENGEVVHG DAILGSLAAF LHEQKALKGG AIVATVMSNA ALDDYLKAHK 310 320 330 340 350 360 IKLLRSNVGD KYVLEMMKEN GINFGGEQSG HVIFNDYAKT GDGLVTSMQV VAMMLKKGKK 370 380 390 400 410 420 ASEIFGELKP YPQILLNLKI TEKKPLDKIE GLKELEASLA KEGIRSLFRY SGTENLIRLL 430 440 LEGKNQTLVE KRMDEVEKFF VKALNA

References

[1]

"Genome sequence of Campylobacter concisus 13826 isolated from human feces." Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., On S., Nelson K.E. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 13826.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000792 Genomic DNA. Translation: EAT99044.1.
RefSeq	YP_001465966.1. NC_009802.1.
3D structure databases
ProteinModelPortal	A7ZB08.
ModBase	Search...
Protein-protein interaction databases
STRING	A7ZB08.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5597052.
GenomeReviews	Gene locus Ccon26_00450 in contig CP000792_GR.
KEGG	cco:CCC13826_1807.
PATRIC	20026229. VBICamCon95352_0083.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	IGSAKRI.
ProtClustDB	PRK14324.
Enzyme and pathway databases
BioCyc	CCON360104:CCC13826_1807-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 2 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_CAMC1

Accession

Primary (citable) accession number: A7ZB08

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	October 23, 2007
Last modified:	January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program