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Protein

Nucleoid occlusion protein

Gene

noc

Organism
Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42) (Bacillus amyloliquefaciens subsp. plantarum)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi148 – 167H-T-H motifUniRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processCell cycle, Cell division, Septation

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoid occlusion proteinUniRule annotation
Short name:
NocUniRule annotation
Gene namesi
Name:nocUniRule annotation
Ordered Locus Names:RBAM_038090
OrganismiBacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42) (Bacillus amyloliquefaciens subsp. plantarum)
Taxonomic identifieri326423 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus amyloliquefaciens group
Proteomesi

Subcellular locationi

  • nucleoid UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003466161 – 283Nucleoid occlusion proteinAdd BLAST283

Structurei

3D structure databases

ProteinModelPortaliA7ZAV8
SMRiA7ZAV8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ParB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1475 LUCA
HOGENOMiHOG000088074
KOiK03497
OMAiSQSYVAN

Family and domain databases

HAMAPiMF_02015 ParB_Noc, 1 hit
InterProiView protein in InterPro
IPR023705 Nucleoid_occlusion_protein
IPR004437 ParB/RepB/Spo0J
IPR003115 ParB/Sulfiredoxin_dom
IPR036086 ParB/Sulfiredoxin_sf
PfamiView protein in Pfam
PF02195 ParBc, 1 hit
SMARTiView protein in SMART
SM00470 ParB, 1 hit
SUPFAMiSSF110849 SSF110849, 1 hit
TIGRFAMsiTIGR04285 nucleoid_noc, 1 hit
TIGR00180 parB_part, 1 hit

Sequencei

Sequence statusi: Complete.

A7ZAV8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKHSFSRFFG FGEKEEEPEI AEHDTNKEEI LEIPVHAIVP NRFQPRTIFS
60 70 80 90 100
DEKIKELAMT IHTHGIIQPI VVRHTEDEGQ YELIAGERRW RAVQTLEWEK
110 120 130 140 150
IPAIIKDFSD TETASVALIE NLQREELSSI EEAHAYARLL ELHDLTQEAL
160 170 180 190 200
AQRLGKGQST IANKLRLLKL PEPVQDAIME KKITERHARA LIPLKQPEFQ
210 220 230 240 250
VTLLAEIIEK SLNVKQTEDR VVKMLEQNKQ KPKPRRKAFS RDTRIAMNTI
260 270 280
RQSLSMVEDS GVRLNTEEEE FEEYIQLTIR IPK
Length:283
Mass (Da):32,901
Last modified:October 23, 2007 - v1
Checksum:i8AEF68E728688D1B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000560 Genomic DNA Translation: ABS76134.1
RefSeqiWP_007409900.1, NC_009725.1

Genome annotation databases

EnsemblBacteriaiABS76134; ABS76134; RBAM_038090
KEGGibay:RBAM_038090

Entry informationi

Entry nameiNOC_BACVZ
AccessioniPrimary (citable) accession number: A7ZAV8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: October 23, 2007
Last modified: May 23, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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