Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Nucleoid occlusion protein

Gene

noc

Organism
Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42) (Bacillus amyloliquefaciens subsp. plantarum)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi148 – 167H-T-H motifUniRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, Septation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoid occlusion proteinUniRule annotation
Short name:
NocUniRule annotation
Gene namesi
Name:nocUniRule annotation
Ordered Locus Names:RBAM_038090
OrganismiBacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42) (Bacillus amyloliquefaciens subsp. plantarum)
Taxonomic identifieri326423 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001120 Componenti: Chromosome

Subcellular locationi

  • Cytoplasmnucleoid UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003466161 – 283Nucleoid occlusion proteinAdd BLAST283

Interactioni

Protein-protein interaction databases

STRINGi326423.RBAM_038090.

Structurei

3D structure databases

ProteinModelPortaliA7ZAV8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ParB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1475. LUCA.
HOGENOMiHOG000088074.
KOiK03497.
OMAiSQSYVAN.

Family and domain databases

HAMAPiMF_02015. ParB_Noc. 1 hit.
InterProiIPR023705. Nucleoid_occlusion_protein.
IPR004437. ParB/RepB/Spo0J.
IPR003115. ParB/Sulfiredoxin_dom.
[Graphical view]
PfamiPF02195. ParBc. 1 hit.
[Graphical view]
SMARTiSM00470. ParB. 1 hit.
[Graphical view]
SUPFAMiSSF110849. SSF110849. 1 hit.
TIGRFAMsiTIGR04285. nucleoid_noc. 1 hit.
TIGR00180. parB_part. 1 hit.

Sequencei

Sequence statusi: Complete.

A7ZAV8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKHSFSRFFG FGEKEEEPEI AEHDTNKEEI LEIPVHAIVP NRFQPRTIFS
60 70 80 90 100
DEKIKELAMT IHTHGIIQPI VVRHTEDEGQ YELIAGERRW RAVQTLEWEK
110 120 130 140 150
IPAIIKDFSD TETASVALIE NLQREELSSI EEAHAYARLL ELHDLTQEAL
160 170 180 190 200
AQRLGKGQST IANKLRLLKL PEPVQDAIME KKITERHARA LIPLKQPEFQ
210 220 230 240 250
VTLLAEIIEK SLNVKQTEDR VVKMLEQNKQ KPKPRRKAFS RDTRIAMNTI
260 270 280
RQSLSMVEDS GVRLNTEEEE FEEYIQLTIR IPK
Length:283
Mass (Da):32,901
Last modified:October 23, 2007 - v1
Checksum:i8AEF68E728688D1B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000560 Genomic DNA. Translation: ABS76134.1.
RefSeqiWP_007409900.1. NC_009725.1.

Genome annotation databases

EnsemblBacteriaiABS76134; ABS76134; RBAM_038090.
KEGGibay:RBAM_038090.
PATRICi18752844. VBIBacAmy31356_3864.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000560 Genomic DNA. Translation: ABS76134.1.
RefSeqiWP_007409900.1. NC_009725.1.

3D structure databases

ProteinModelPortaliA7ZAV8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi326423.RBAM_038090.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABS76134; ABS76134; RBAM_038090.
KEGGibay:RBAM_038090.
PATRICi18752844. VBIBacAmy31356_3864.

Phylogenomic databases

eggNOGiCOG1475. LUCA.
HOGENOMiHOG000088074.
KOiK03497.
OMAiSQSYVAN.

Family and domain databases

HAMAPiMF_02015. ParB_Noc. 1 hit.
InterProiIPR023705. Nucleoid_occlusion_protein.
IPR004437. ParB/RepB/Spo0J.
IPR003115. ParB/Sulfiredoxin_dom.
[Graphical view]
PfamiPF02195. ParBc. 1 hit.
[Graphical view]
SMARTiSM00470. ParB. 1 hit.
[Graphical view]
SUPFAMiSSF110849. SSF110849. 1 hit.
TIGRFAMsiTIGR04285. nucleoid_noc. 1 hit.
TIGR00180. parB_part. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNOC_BACVZ
AccessioniPrimary (citable) accession number: A7ZAV8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: October 23, 2007
Last modified: November 30, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.