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A7Z8F5 (ALLB_BACA2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Allantoinase

EC=3.5.2.5
Alternative name(s):
Allantoin-utilizing enzyme
Gene names
Name:allB
Synonyms:pucH
Ordered Locus Names:RBAM_029500
OrganismBacillus amyloliquefaciens subsp. plantarum (strain DSM 23117 / BGSC 10A6 / FZB42) [Complete proteome] [HAMAP]
Taxonomic identifier326423 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length454 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring By similarity. HAMAP-Rule MF_01645

Catalytic activity

(S)-allantoin + H2O = allantoate. HAMAP-Rule MF_01645

Cofactor

Binds 2 zinc ions per subunit By similarity. HAMAP-Rule MF_01645

Pathway

Nitrogen metabolism; (S)-allantoin degradation; allantoate from (S)-allantoin: step 1/1. HAMAP-Rule MF_01645

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01645

Post-translational modification

Carbamylation allows a single lysine to coordinate two zinc ions By similarity. HAMAP-Rule MF_01645

Sequence similarities

Belongs to the DHOase family. Allantoinase subfamily.

Ontologies

Keywords
   Biological processPurine metabolism
   LigandMetal-binding
Zinc
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processallantoin catabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

purine nucleobase metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionallantoinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

cobalt ion binding

Inferred from electronic annotation. Source: InterPro

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 454454Allantoinase HAMAP-Rule MF_01645
PRO_0000317668

Sites

Metal binding601Zinc 1 By similarity
Metal binding621Zinc 1 By similarity
Metal binding1471Zinc 1; via carbamate group By similarity
Metal binding1471Zinc 2; via carbamate group By similarity
Metal binding1831Zinc 2 By similarity
Metal binding2391Zinc 2 By similarity
Metal binding3121Zinc 1 By similarity

Amino acid modifications

Modified residue1471N6-carboxylysine By similarity

Sequences

Sequence LengthMass (Da)Tools
A7Z8F5 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: BCA128C60A38F03C

FASTA45449,454
        10         20         30         40         50         60 
MAYDVIVKGA KAVRKGGTER ADIAVKDGKI ALIGPGIDEN AEQVVQADGM YVFPGAVDCH 

        70         80         90        100        110        120 
VHFNEPGREE WEGIETGSNM LAAGGCTSYF DMPLNCIPST VTAENLLAKA EIAERKSAVD 

       130        140        150        160        170        180 
FALWGGLMPG YTEHIRPMAE AGAIGFKAFL SKSGTDEFQS ADERTLLKGM KEIAACGKVL 

       190        200        210        220        230        240 
ALHAESDALT RFLEAEYALQ GKIDVRAYAS SRPEEAECEA VQRAIEYARA TGCALHFVHI 

       250        260        270        280        290        300 
STKRAVLSIQ QAKKDGLDVT VETCPHYLLF SFEDFLKKGA AAKCAPPLRS EADKEELIGV 

       310        320        330        340        350        360 
LAEGLIDMVS SDHSPCHPSL KREDNMFLSW GGISGGQFTL LGMIQLAIDH GIPFEHVARW 

       370        380        390        400        410        420 
TAEAPAKRFG LTNKGRLEEG FDADFAIVRP EPFTVTKETM FSKHKQSLYE GHTFPYRIAA 

       430        440        450 
TYSKGRCVYQ DGGRKQSGAF GTFLKPSEIK EPIL 

« Hide

References

[1]"Comparative analysis of the complete genome sequence of the plant growth-promoting bacterium Bacillus amyloliquefaciens FZB42."
Chen X.H., Koumoutsi A., Scholz R., Eisenreich A., Schneider K., Heinemeyer I., Morgenstern B., Voss B., Hess W.R., Reva O., Junge H., Voigt B., Jungblut P.R., Vater J., Suessmuth R., Liesegang H., Strittmatter A., Gottschalk G., Borriss R.
Nat. Biotechnol. 25:1007-1014(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 23117 / BGSC 10A6 / FZB42.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000560 Genomic DNA. Translation: ABS75281.1.
RefSeqYP_001422512.1. NC_009725.1.

3D structure databases

ProteinModelPortalA7Z8F5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING326423.RBAM_029500.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABS75281; ABS75281; RBAM_029500.
GeneID5462691.
KEGGbay:RBAM_029500.
PATRIC18751084. VBIBacAmy31356_2989.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0044.
HOGENOMHOG000219146.
KOK01466.
OMACSPWEGH.
OrthoDBEOG6KHFW6.

Enzyme and pathway databases

BioCycBAMY326423:GCM4-2948-MONOMER.
UniPathwayUPA00395; UER00653.

Family and domain databases

Gene3D2.30.40.10. 2 hits.
HAMAPMF_01645. Hydantoinase.
InterProIPR017593. Allantoinase.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
SUPFAMSSF51338. SSF51338. 2 hits.
TIGRFAMsTIGR03178. allantoinase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameALLB_BACA2
AccessionPrimary (citable) accession number: A7Z8F5
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: October 23, 2007
Last modified: May 14, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways