Reviewed, UniProtKB/Swiss-Prot A7Z848 (G6PI_BACA2)

Names and origin

Protein names

Recommended name:
    Glucose-6-phosphate isomerase
      Short name=GPI
    EC=5.3.1.9
Alternative name(s):
    Phosphoglucose isomerase
      Short name=PGI
    Phosphohexose isomerase
      Short name=PHI

Gene names

Name:	pgi
Ordered Locus Names:	RBAM_028430

Organism

Bacillus amyloliquefaciens (strain FZB42) [Complete proteome] [HAMAP]

Taxonomic identifier

326423 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	450 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473
Pathway	Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_00473 Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: HAMAP glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 450	450	Glucose-6-phosphate isomerase HAMAP MF_00473		PRO_1000013939
Sites
	Active site	290	1	Proton donor By similarity
	Active site	311	1	By similarity
	Active site	425	1	By similarity
Amino acid modifications
	Modified residue	38	1	Phosphothreonine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A7Z848-1 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: 81DEDEC349152C0E	FASTA	450	50,600
	10 20 30 40 50 60 MTHVRFDYSR ALPFFNEHEL TYARDFVKTA HHNIHEKTGA GSDFLGWVDL PENYDKEEFA 70 80 90 100 110 120 RIKKSAEKIK SDSDVLLVVG IGGSYLGARA AIEALNHSFY NVLPKDKRKN PQVIFIGNNI 130 140 150 160 170 180 SSTYMKDVMD LLEDADFSIN VISKSGTTTE PAIAFRIFRK LLEEKYGKEE AKARIYATTD 190 200 210 220 230 240 KERGALKTLS NEEGFESFVI PDDVGGRFSV LTAVGLLPIA VSGADIDEMM KGALDASKDF 250 260 270 280 290 300 SSSELEENAA YQYAVVRNVL YNKGRTIEML INYEPALQYF AEWWKQLFGE SEGKDEKGIY 310 320 330 340 350 360 PSSANFSTDL HSLGQYVQEG RRDLFETVLN VEKPKHELTI EEAENDLDGL NYLAGKTVDF 370 380 390 400 410 420 VNKKAFEGTM LAHTDGKVPN LIVNIPELNA YTFGYLVYFF EKAVAMSGYL LGVNPFDQPG 430 440 450 VEAYKVNMFA LLGKPGFEEK KAELEKRLEK

References

[1]

"Comparative analysis of the complete genome sequence of the plant growth-promoting bacterium Bacillus amyloliquefaciens FZB42." Chen X.H., Koumoutsi A., Scholz R., Eisenreich A., Schneider K., Heinemeyer I., Morgenstern B., Voss B., Hess W.R., Reva O., Junge H., Voigt B., Jungblut P.R., Vater J., Suessmuth R., Liesegang H., Strittmatter A., Gottschalk G., Borriss R. Nat. Biotechnol. 25:1007-1014(2007) [PubMed: 17704766] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000560 Genomic DNA. Translation: ABS75174.1.
RefSeq	YP_001422405.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A7Z848.
Genome annotation databases
GeneID	5460452.
GenomeReviews	Gene locus RBAM_028430 in contig CP000560_GR.
KEGG	bay:RBAM_028430.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	NPRKNVI.
Family and domain databases
HAMAP	MF_00473. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI_BACA2

Accession

Primary (citable) accession number: A7Z848

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 23, 2007
Last modified:	November 3, 2009
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)