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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42) (Bacillus amyloliquefaciens subsp. plantarum)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei290Proton donorUniRule annotation1
Active sitei311UniRule annotation1
Active sitei425UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181
UPA00138

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:RBAM_028430
OrganismiBacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42) (Bacillus amyloliquefaciens subsp. plantarum)
Taxonomic identifieri326423 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus amyloliquefaciens group
Proteomesi
  • UP000001120 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000139391 – 450Glucose-6-phosphate isomeraseAdd BLAST450

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei38PhosphothreonineUniRule annotation1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiA7Z848

Structurei

3D structure databases

ProteinModelPortaliA7Z848
SMRiA7Z848
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QYV Bacteria
COG0166 LUCA
HOGENOMiHOG000100403
KOiK01810
OMAiSFIIPDD

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 2 hits
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

A7Z848-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTHVRFDYSR ALPFFNEHEL TYARDFVKTA HHNIHEKTGA GSDFLGWVDL
60 70 80 90 100
PENYDKEEFA RIKKSAEKIK SDSDVLLVVG IGGSYLGARA AIEALNHSFY
110 120 130 140 150
NVLPKDKRKN PQVIFIGNNI SSTYMKDVMD LLEDADFSIN VISKSGTTTE
160 170 180 190 200
PAIAFRIFRK LLEEKYGKEE AKARIYATTD KERGALKTLS NEEGFESFVI
210 220 230 240 250
PDDVGGRFSV LTAVGLLPIA VSGADIDEMM KGALDASKDF SSSELEENAA
260 270 280 290 300
YQYAVVRNVL YNKGRTIEML INYEPALQYF AEWWKQLFGE SEGKDEKGIY
310 320 330 340 350
PSSANFSTDL HSLGQYVQEG RRDLFETVLN VEKPKHELTI EEAENDLDGL
360 370 380 390 400
NYLAGKTVDF VNKKAFEGTM LAHTDGKVPN LIVNIPELNA YTFGYLVYFF
410 420 430 440 450
EKAVAMSGYL LGVNPFDQPG VEAYKVNMFA LLGKPGFEEK KAELEKRLEK
Length:450
Mass (Da):50,600
Last modified:October 23, 2007 - v1
Checksum:i81DEDEC349152C0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000560 Genomic DNA Translation: ABS75174.1
RefSeqiWP_007408647.1, NC_009725.1

Genome annotation databases

EnsemblBacteriaiABS75174; ABS75174; RBAM_028430
KEGGibay:RBAM_028430

Similar proteinsi

Entry informationi

Entry nameiG6PI_BACVZ
AccessioniPrimary (citable) accession number: A7Z848
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 23, 2007
Last modified: May 23, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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