Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A7Z7V7

- SYL_BACA2

UniProt

A7Z7V7 - SYL_BACA2

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Leucine--tRNA ligase

Gene

leuS

Organism
Bacillus amyloliquefaciens subsp. plantarum (strain DSM 23117 / BGSC 10A6 / FZB42)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei579 – 5791ATPUniRule annotation

GO - Molecular functioni

  1. aminoacyl-tRNA editing activity Source: InterPro
  2. ATP binding Source: UniProtKB-HAMAP
  3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBAMY326423:GCM4-2723-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine--tRNA ligaseUniRule annotation (EC:6.1.1.4UniRule annotation)
Alternative name(s):
Leucyl-tRNA synthetaseUniRule annotation
Short name:
LeuRSUniRule annotation
Gene namesi
Name:leuSUniRule annotation
Ordered Locus Names:RBAM_027250
OrganismiBacillus amyloliquefaciens subsp. plantarum (strain DSM 23117 / BGSC 10A6 / FZB42)
Taxonomic identifieri326423 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000001120: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 804804Leucine--tRNA ligasePRO_1000009291Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi326423.RBAM_027250.

Structurei

3D structure databases

ProteinModelPortaliA7Z7V7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi40 – 5112"HIGH" regionAdd
BLAST
Motifi576 – 5805"KMSKS" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0495.
HOGENOMiHOG000200748.
KOiK01869.
OMAiHISHELW.
OrthoDBiEOG63Z74X.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 2 hits.
3.90.740.10. 1 hit.
HAMAPiMF_00049_B. Leu_tRNA_synth_B.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR015413. Methionyl/Leucyl_tRNA_Synth.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PfamiPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 1 hit.
PF13603. tRNA-synt_1_2. 1 hit.
PF09334. tRNA-synt_1g. 1 hit.
[Graphical view]
PRINTSiPR00985. TRNASYNTHLEU.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsiTIGR00396. leuS_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7Z7V7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSFQHEKIEK KWQNYWLDHK TFAVSEENDK PKFYALDMFP YPSGAGLHVG
60 70 80 90 100
HPEGYTATDI LSRMRRMQGY NVLHPMGWDA FGLPAEQYAL DTGNDPAEFT
110 120 130 140 150
KQNIDNFRRQ IQSLGFSYDW DREINTTDPD YYKWTQWIFT KLYEKGLAYV
160 170 180 190 200
DEVPVNWCPA LGTVLANEEV IDGKSERGGH PVERRPMRQW MLKITAYADR
210 220 230 240 250
LLEDLEDLDW PESIKDMQRN WIGRSEGANV HFAIDGTDDT FTVFTTRPDT
260 270 280 290 300
LFGAAYAVLA PEHELVEAIT TPEQKEAVDA YVKEVQAKSD LERTDLAKTK
310 320 330 340 350
TGVFTGAYAV NPANGEKLPI WIADYVLASY GTGAVMAVPA HDERDFEFAK
360 370 380 390 400
VFSLPVKEVV KGGNTEEEAY TGDGEHVNSG FLNGLKKAEA IEKMIAWLEE
410 420 430 440 450
TKNGEKKVTY RLRDWLFSRQ RYWGEPIPVI HWEDGTSTAV PAEELPLILP
460 470 480 490 500
KTDEIKPSGT GESPLANIKE WVEVTDPETG KKGRRETNTM PQWAGSCWYF
510 520 530 540 550
LRFIDPKNPD QLASPEKLDK WLPVDIYIGG AEHAVLHLLY ARFWHKFLYD
560 570 580 590 600
IGVVPTKEPF QKLYNQGMIL GENNEKMSKS RGNVVNPDEI VASHGADTLR
610 620 630 640 650
LYEMFMGPLD ASIAWSESGL DGARRFLDRV WRLFIEENGE LTGKVTEGAG
660 670 680 690 700
ETLERVYHET VMKVTENFEA LRFNTGISQL MVFINEAYKA NELPREYIEG
710 720 730 740 750
FVKLLSPIAP HLAEELWEKL GHEGSIAYEA WPAYDESKLV DDEVEIVVQL
760 770 780 790 800
NGKVKAKLMV PADADKAALE QLAQADEKVK EQLEGKTIRK IIAVPGKLVN

IVAN
Length:804
Mass (Da):91,270
Last modified:October 23, 2007 - v1
Checksum:i37CC64858244D4EF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000560 Genomic DNA. Translation: ABS75083.1.
RefSeqiYP_001422314.1. NC_009725.1.

Genome annotation databases

EnsemblBacteriaiABS75083; ABS75083; RBAM_027250.
GeneIDi5462049.
KEGGibay:RBAM_027250.
PATRICi18750606. VBIBacAmy31356_2776.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000560 Genomic DNA. Translation: ABS75083.1 .
RefSeqi YP_001422314.1. NC_009725.1.

3D structure databases

ProteinModelPortali A7Z7V7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 326423.RBAM_027250.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABS75083 ; ABS75083 ; RBAM_027250 .
GeneIDi 5462049.
KEGGi bay:RBAM_027250.
PATRICi 18750606. VBIBacAmy31356_2776.

Phylogenomic databases

eggNOGi COG0495.
HOGENOMi HOG000200748.
KOi K01869.
OMAi HISHELW.
OrthoDBi EOG63Z74X.

Enzyme and pathway databases

BioCyci BAMY326423:GCM4-2723-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 2 hits.
3.90.740.10. 1 hit.
HAMAPi MF_00049_B. Leu_tRNA_synth_B.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR015413. Methionyl/Leucyl_tRNA_Synth.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
Pfami PF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 1 hit.
PF13603. tRNA-synt_1_2. 1 hit.
PF09334. tRNA-synt_1g. 1 hit.
[Graphical view ]
PRINTSi PR00985. TRNASYNTHLEU.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 23117 / BGSC 10A6 / FZB42.

Entry informationi

Entry nameiSYL_BACA2
AccessioniPrimary (citable) accession number: A7Z7V7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 23, 2007
Last modified: November 26, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3