Reviewed, UniProtKB/Swiss-Prot A7Z7M2 (ACKA_BACA2)

Names and origin

Protein names

Recommended name:
    Acetate kinase
    EC=2.7.2.1
Alternative name(s):
    Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	RBAM_026400

Organism

Bacillus amyloliquefaciens (strain FZB42) [Complete proteome] [HAMAP]

Taxonomic identifier

326423 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	395 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 395	395	Acetate kinase HAMAP MF_00020		PRO_1000002208

Sequences

	Sequence		Length	Mass (Da)
	A7Z7M2-1 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: FB7A4418A98CEFB9	FASTA	395	43,275
	10 20 30 40 50 60 MSKIIAINAG SSSLKFQLFE MPSEKVLTKG LVERIGIADS VFTISVNGEK NTEVTDIPDH 70 80 90 100 110 120 AVAVKMLLHK LTEFGIIKDL NEIDGIGHRV VHGGEKFSDS VLLTDETIRE IEEISELAPL 130 140 150 160 170 180 HNPANIVGIK AFKEVLPNVP AVAVFDTAFH QTMPEQSYLY SLPYEYYEKY GIRKYGFHGT 190 200 210 220 230 240 SHKYVTQRAA ELLGRPLEDL RLISCHLGNG ASIAAVEGGK SIDTSMGFTP LAGVAMGTRS 250 260 270 280 290 300 GNIDPALIPY IMEKTDQTAD EVLNTLNKKS GLLGVSGFSS DLRDIVEASK EGNERAETAL 310 320 330 340 350 360 EVFASRIHKY IGSYAARMSG VDAIIFTAGI GENSVEVRER VLRGLEFMGV YWDPALNNVR 370 380 390 GEEAFISYPH SPVKVMIIPT DEEVMIARDV VRLAQ

References

[1]

"Comparative analysis of the complete genome sequence of the plant growth-promoting bacterium Bacillus amyloliquefaciens FZB42." Chen X.H., Koumoutsi A., Scholz R., Eisenreich A., Schneider K., Heinemeyer I., Morgenstern B., Voss B., Hess W.R., Reva O., Junge H., Voigt B., Jungblut P.R., Vater J., Suessmuth R., Liesegang H., Strittmatter A., Gottschalk G., Borriss R. Nat. Biotechnol. 25:1007-1014(2007) [PubMed: 17704766] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000560 Genomic DNA. Translation: ABS74998.1.
RefSeq	YP_001422229.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A7Z7M2.
Genome annotation databases
GeneID	5461724.
GenomeReviews	Gene locus RBAM_026400 in contig CP000560_GR.
KEGG	bay:RBAM_026400.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	SSDFRDV.
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_BACA2

Accession

Primary (citable) accession number: A7Z7M2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 23, 2007
Last modified:	November 3, 2009
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)