A7Z640 (KCY_BACA2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase
Short name=CK
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	RBAM_021040

Organism

Bacillus amyloliquefaciens (strain FZB42) [Complete proteome] [HAMAP]

Taxonomic identifier

326423 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	224 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity HAMAP MF_00238.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 224	224	Cytidylate kinase HAMAP MF_00238		PRO_1000048182
Regions
	Nucleotide binding	11 – 19	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	A7Z640 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: B0A2DD0172473278	FASTA	224	24,915
	10 20 30 40 50 60 MDKKLSIAID GPAAAGKSTV AKIVAEKKSY VYIDTGAMYR AITYTALKQN ADLTDEAALT 70 80 90 100 110 120 ELLKRTEIEL VSVPEGQIVL VNGEDVTEEI RKDEVSNQVS IAAKHKGVRE EMVKRQQQLG 130 140 150 160 170 180 QKGGVVMDGR DIGTHVLPDA EVKIFLLASV EERAKRRYEE NKKKGYDVNY ETLIEEIARR 190 200 210 220 DKLDSEREVS PLRKAEDAIE IDTTSLSIAE VAGKILEIVE QKSR

References

[1]

"Comparative analysis of the complete genome sequence of the plant growth-promoting bacterium Bacillus amyloliquefaciens FZB42." Chen X.H., Koumoutsi A., Scholz R., Eisenreich A., Schneider K., Heinemeyer I., Morgenstern B., Voss B., Hess W.R., Reva O., Junge H., Voigt B., Jungblut P.R., Vater J., Suessmuth R., Liesegang H., Strittmatter A., Gottschalk G., Borriss R. Nat. Biotechnol. 25:1007-1014(2007) [PubMed: 17704766] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: FZB42.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000560 Genomic DNA. Translation: ABS74466.1.
RefSeq	YP_001421697.1. NC_009725.1.
3D structure databases
ProteinModelPortal	A7Z640.
SMR	A7Z640. Positions 3-222.
ModBase	Search...
Protein-protein interaction databases
STRING	A7Z640.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000004930; EBBACP00000004808; EBBACG00000004922.
GeneID	5462252.
GenomeReviews	Gene locus RBAM_021040 in contig CP000560_GR.
KEGG	bay:RBAM_021040.
PATRIC	18749290. VBIBacAmy31356_2121.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0283.
GeneTree	EBGT00050000002974.
HOGENOM	HBG354377.
OMA	DIGTVIC.
ProtClustDB	PRK00023.
Enzyme and pathway databases
BioCyc	BAMY326423:RBAM_021040-MONOMER.
Family and domain databases
HAMAP	MF_00238. Cytidyl_kinase_type1. [Tree]
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kinase_dom. [Graphical view]
KO	K00945.
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00017. Cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_BACA2

Accession

Primary (citable) accession number: A7Z640

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 23, 2007
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program