A7Z5S1 (MSRB_BACA2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrB
EC=1.8.4.12

Alternative name(s):
Peptide-methionine (R)-S-oxide reductase

Gene names

Name:	msrB
Ordered Locus Names:	RBAM_019850

Organism

Bacillus amyloliquefaciens (strain FZB42) [Complete proteome] [HAMAP]

Taxonomic identifier

326423 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	144 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Sequence similarities	Belongs to the MsrB Met sulfoxide reductase family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 144	144	Peptide methionine sulfoxide reductase MsrB HAMAP MF_01400		PRO_1000068263
Sites
	Active site	116	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	A7Z5S1 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: 04C1BD1B5AAA189C	FASTA	144	16,555
	10 20 30 40 50 60 MAFNKEEKIK SLNRMQYEVT QNNGTEPPFQ NEFWDHKEEG LYVDIVSGKP LFTSLDKFDS 70 80 90 100 110 120 HCGWPSFTKP IEEEEVDEKL DTSHGMIRTE VRSKTADSHL GHVFNDGPGP SGLRYCINSA 130 140 ALRFIPKDKL KEEGYEACLH LFEK

References

[1]

"Comparative analysis of the complete genome sequence of the plant growth-promoting bacterium Bacillus amyloliquefaciens FZB42." Chen X.H., Koumoutsi A., Scholz R., Eisenreich A., Schneider K., Heinemeyer I., Morgenstern B., Voss B., Hess W.R., Reva O., Junge H., Voigt B., Jungblut P.R., Vater J., Suessmuth R., Liesegang H., Strittmatter A., Gottschalk G., Borriss R. Nat. Biotechnol. 25:1007-1014(2007) [PubMed: 17704766] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: FZB42.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000560 Genomic DNA. Translation: ABS74347.1.
RefSeq	YP_001421578.1. NC_009725.1.
3D structure databases
ProteinModelPortal	A7Z5S1.
SMR	A7Z5S1. Positions 1-144.
ModBase	Search...
Protein-protein interaction databases
STRING	A7Z5S1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000006596; EBBACP00000006474; EBBACG00000006588.
GeneID	5462773.
GenomeReviews	Gene locus RBAM_019850 in contig CP000560_GR.
KEGG	bay:RBAM_019850.
PATRIC	18749046. VBIBacAmy31356_1999.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0229.
GeneTree	EBGT00050000000580.
HOGENOM	HBG715255.
OMA	FTDGPVD.
ProtClustDB	PRK00222.
Enzyme and pathway databases
BioCyc	BAMY326423:RBAM_019850-MONOMER.
Family and domain databases
HAMAP	MF_01400. MsrB. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. IPR011057. Mss4-like. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
KO	K07305.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
SUPFAM	SSF51316. Mss4_like. 1 hit.
TIGRFAMs	TIGR00357. TIGR00357. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MSRB_BACA2

Accession

Primary (citable) accession number: A7Z5S1

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	October 23, 2007
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program