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A7Z4M9 (SUCC_BACA2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Succinyl-CoA ligase [ADP-forming] subunit beta

EC=6.2.1.5
Alternative name(s):
Succinyl-CoA synthetase subunit beta
Short name=SCS-beta
Gene names
Name:sucC
Ordered Locus Names:RBAM_015920
OrganismBacillus amyloliquefaciens subsp. plantarum (strain DSM 23117 / BGSC 10A6 / FZB42) [Complete proteome] [HAMAP]
Taxonomic identifier326423 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length385 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + succinate + CoA = ADP + phosphate + succinyl-CoA. HAMAP-Rule MF_00558

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity.

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1. HAMAP-Rule MF_00558

Subunit structure

Heterotetramer of two alpha and two beta subunits By similarity.

Sequence similarities

Belongs to the succinate/malate CoA ligase beta subunit family.

Contains 1 ATP-grasp domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 385385Succinyl-CoA ligase [ADP-forming] subunit beta HAMAP-Rule MF_00558
PRO_1000082004

Regions

Domain9 – 244236ATP-grasp
Nucleotide binding35 – 10874ATP By similarity

Sites

Metal binding1971Magnesium or manganese By similarity
Metal binding1991Magnesium or manganese By similarity

Amino acid modifications

Modified residue2201Phosphoserine By similarity

Sequences

Sequence LengthMass (Da)Tools
A7Z4M9 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: A477F07640FF24E2

FASTA38541,514
        10         20         30         40         50         60 
MNIHEYQGKE VLRKYGVSVP EGKVAFTAEE AVEKAESLSS SVYVVKAQIH AGGRGKAGGV 

        70         80         90        100        110        120 
KIAKTKDEVK EYAEELLGKT LVTHQTGPDG QVIKRLLIEE GCDIKKEYYV GLVLDRATSR 

       130        140        150        160        170        180 
IVLMASEEGG TEIEEVAEKT PEKIKKAVID PAVGLQGYQA REIAFAINIP KELVGKAAKF 

       190        200        210        220        230        240 
MLGLYKAFVE KDCSIAEINP LVVTGDGNVM ALDAKLNFDS NALYRQKDIM EYRDLDEEDP 

       250        260        270        280        290        300 
KEIEASKYDL SYISLDGNIG CMVNGAGLAM STMDIIKHYG GEPANFLDVG GGATAEKVTE 

       310        320        330        340        350        360 
AFKIILSDQN VKGIFVNIFG GIMKCDVIAE GVVEATRQVG LTLPLVVRLE GTNVDLGKKI 

       370        380 
LNESGLNITS AESMADGAQK IVSLV 

« Hide

References

[1]"Comparative analysis of the complete genome sequence of the plant growth-promoting bacterium Bacillus amyloliquefaciens FZB42."
Chen X.H., Koumoutsi A., Scholz R., Eisenreich A., Schneider K., Heinemeyer I., Morgenstern B., Voss B., Hess W.R., Reva O., Junge H., Voigt B., Jungblut P.R., Vater J., Suessmuth R., Liesegang H., Strittmatter A., Gottschalk G., Borriss R.
Nat. Biotechnol. 25:1007-1014(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 23117 / BGSC 10A6 / FZB42.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000560 Genomic DNA. Translation: ABS73955.1.
RefSeqYP_001421186.1. NC_009725.1.

3D structure databases

ProteinModelPortalA7Z4M9.
SMRA7Z4M9. Positions 1-385.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING326423.RBAM_015920.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABS73955; ABS73955; RBAM_015920.
GeneID5463277.
KEGGbay:RBAM_015920.
PATRIC18748250. VBIBacAmy31356_1601.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0045.
HOGENOMHOG000007059.
KOK01903.
OMAAAGRICK.
OrthoDBEOG644ZT0.

Enzyme and pathway databases

BioCycBAMY326423:GCM4-1590-MONOMER.
UniPathwayUPA00223; UER00999.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.261. 1 hit.
HAMAPMF_00558. Succ_CoA_beta.
InterProIPR011761. ATP-grasp.
IPR013650. ATP-grasp_succ-CoA_synth-type.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005811. CoA_ligase.
IPR017866. Succ-CoA_synthase_bsu_CS.
IPR005809. Succ_CoA_synthase_bsu.
IPR016102. Succinyl-CoA_synth-like.
[Graphical view]
PANTHERPTHR11815. PTHR11815. 1 hit.
PfamPF08442. ATP-grasp_2. 1 hit.
PF00549. Ligase_CoA. 1 hit.
[Graphical view]
PIRSFPIRSF001554. SucCS_beta. 1 hit.
SUPFAMSSF52210. SSF52210. 1 hit.
TIGRFAMsTIGR01016. sucCoAbeta. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS01217. SUCCINYL_COA_LIG_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSUCC_BACA2
AccessionPrimary (citable) accession number: A7Z4M9
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: October 23, 2007
Last modified: May 14, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways